| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 08-Aug-2021 | draw |  FC Lorient | 1-1 | home |
| 21-Aug-2021 | draw |  Lille OSC | 1-1 | home |
| 28-Aug-2021 | lose |  Olympique Marseille | 3-1 | away |
| 12-Sep-2021 | lose |  Montpellier HSC | 2-0 | away |
| 18-Sep-2021 | lose |  Girondins De Bordeaux | 1-2 | home |
| 22-Sep-2021 | lose |  AS Monaco | 3-1 | away |
| 25-Sep-2021 | lose |  OGC Nice | 0-3 | home |
| 03-Oct-2021 | draw |  Olympique Lyonnais | 1-1 | home |
| 17-Oct-2021 | lose |  RC Strasbourg | 5-1 | away |
| 22-Oct-2021 | draw |  Angers SCO | 2-2 | home |
| 30-Oct-2021 | draw |  FC Metz | 1-1 | away |
| 07-Nov-2021 | win | Clermont Foot | 3-2 | home |
| 01-Dec-2021 | lose | Stade Brestois 29 | 1-0 | away |
| 05-Dec-2021 | lose |  Stade Rennes | 0-5 | home |
| 11-Dec-2021 | lose | Stade Reims | 2-0 | away |
| 22-Dec-2021 | lose |  FC Nantes | 0-1 | home |
| 21-Jan-2022 | lose | Olympique Lyonnais | 1-0 | away |
| 05-Feb-2022 | win | Montpellier HSC | 3-1 | home |
| 13-Feb-2022 | win | Clermont Foot | 1-2 | away |
| 18-Mar-2022 | draw | Troyes AC | 1-1 | home |
| 16-Apr-2022 | win | Stade Brestois 29 | 2-1 | home |
| 20-Apr-2022 | draw | Girondins De Bordeaux | 2-2 | away |
| 23-Apr-2022 | lose | AS Monaco | 1-4 | home |
| 30-Apr-2022 | lose | Stade Rennes | 2-0 | away |
| 14-May-2022 | lose | Stade Reims | 1-2 | home |
| 21-May-2022 | draw | FC Nantes | 1-1 | away |
Overall ( 4 wins,8 draw,14 lost )
Home ( 3 wins,5 draw,6 lost )
Away ( 1 wins,3 draw,8 lost )
OPP = Opposition,
FS = Final score.