| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 22-Aug-2021 | draw |  Olympique Lyonnais | 3-3 | away |
| 29-Aug-2021 | draw |  FC Metz | 2-2 | home |
| 11-Sep-2021 | lose |  Paris Saint-Germain | 4-0 | away |
| 19-Sep-2021 | draw |  Stade Brestois 29 | 1-1 | home |
| 22-Sep-2021 | lose |  Stade Rennes | 6-0 | away |
| 23-Oct-2021 | lose |  FC Nantes | 2-1 | away |
| 31-Oct-2021 | lose |  Olympique Marseille | 0-1 | home |
| 28-Nov-2021 | lose | Stade Reims | 1-0 | away |
| 01-Dec-2021 | draw | RC Lens | 2-2 | home |
| 05-Dec-2021 | lose |  Montpellier HSC | 1-0 | away |
| 16-Jan-2022 | lose |  AS Monaco | 4-0 | away |
| 19-Jan-2022 | lose | RC Strasbourg | 0-2 | home |
| 23-Jan-2022 | win | Stade Rennes | 2-1 | home |
| 27-Feb-2022 | draw |  Girondins De Bordeaux | 1-1 | home |
| 06-Mar-2022 | lose |  Lille OSC | 4-0 | away |
| 13-Mar-2022 | lose |  FC Lorient | 0-2 | home |
| 03-Apr-2022 | lose | FC Nantes | 2-3 | home |
| 09-Apr-2022 | lose | Paris Saint-Germain | 1-6 | home |
| 17-Apr-2022 | draw | FC Metz | 1-1 | away |
| 24-Apr-2022 | draw |  Angers SCO | 2-2 | home |
| 01-May-2022 | lose | Stade Brestois 29 | 2-0 | away |
| 14-May-2022 | lose | RC Strasbourg | 1-0 | away |
| 21-May-2022 | lose | Olympique Lyonnais | 1-2 | home |
Overall ( 1 wins,7 draw,15 lost )
Home ( 1 wins,5 draw,6 lost )
Away ( 0 wins,2 draw,9 lost )
OPP = Opposition,
FS = Final score.