| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 15-Aug-2021 | draw |  Stade Rennes | 1-1 | home |
| 20-Aug-2021 | lose |  Paris Saint-Germain | 2-4 | home |
| 29-Aug-2021 | lose |  RC Strasbourg | 3-1 | away |
| 22-Sep-2021 | lose |  FC Nantes | 3-1 | away |
| 26-Sep-2021 | lose |  FC Metz | 1-2 | home |
| 02-Oct-2021 | lose |  OGC Nice | 2-1 | away |
| 17-Oct-2021 | draw | Stade Reims | 1-1 | home |
| 23-Oct-2021 | draw |  Lille OSC | 1-1 | away |
| 07-Nov-2021 | win |  FC Lorient | 1-2 | away |
| 28-Nov-2021 | win |  Girondins De Bordeaux | 1-2 | away |
| 04-Dec-2021 | win |  Olympique Marseille | 1-2 | away |
| 11-Dec-2021 | lose |  Montpellier HSC | 0-4 | home |
| 09-Jan-2022 | lose | OGC Nice | 0-3 | home |
| 15-Jan-2022 | lose | Paris Saint-Germain | 2-0 | away |
| 06-Feb-2022 | lose | Stade Rennes | 2-0 | away |
| 20-Feb-2022 | draw | Stade Reims | 1-1 | away |
| 27-Feb-2022 | lose | FC Lorient | 0-1 | home |
| 13-Mar-2022 | lose | Olympique Marseille | 1-4 | home |
| 20-Mar-2022 | lose |  Angers SCO | 1-0 | away |
| 10-Apr-2022 | draw | FC Nantes | 1-1 | home |
| 07-May-2022 | lose | RC Strasbourg | 0-1 | home |
| 21-May-2022 | lose | Girondins De Bordeaux | 2-4 | home |
Overall ( 3 wins,5 draw,14 lost )
Home ( 0 wins,3 draw,8 lost )
Away ( 3 wins,2 draw,6 lost )
OPP = Opposition,
FS = Final score.