| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 22-Aug-2021 | win |  Fiorentina | 3-1 | home |
| 29-Aug-2021 | win |  Salernitana | 0-4 | away |
| 12-Sep-2021 | win |  Sassuolo | 2-1 | home |
| 19-Sep-2021 | lose | Hellas Verona | 3-2 | away |
| 23-Sep-2021 | win |  Udinese | 1-0 | home |
| 03-Oct-2021 | win |  Empoli | 2-0 | home |
| 21-Nov-2021 | win |  Genoa | 0-2 | away |
| 28-Nov-2021 | win |  Torino | 1-0 | home |
| 13-Dec-2021 | win | Spezia Calcio | 2-0 | home |
| 18-Dec-2021 | win |  Atalanta | 1-4 | away |
| 22-Dec-2021 | draw |  Sampdoria | 1-1 | home |
| 09-Jan-2022 | lose |  Juventus | 3-4 | home |
| 16-Jan-2022 | win |  Cagliari | 1-0 | home |
| 23-Jan-2022 | win | Empoli | 2-4 | away |
| 13-Feb-2022 | draw | Sassuolo | 2-2 | away |
| 27-Feb-2022 | win | Spezia Calcio | 0-1 | away |
| 05-Mar-2022 | win | Atalanta | 1-0 | home |
| 20-Mar-2022 | win |  SS Lazio | 3-0 | home |
| 03-Apr-2022 | win | Sampdoria | 0-1 | away |
| 20-May-2022 | win | Torino | 0-3 | away |
Overall ( 16 wins,2 draw,2 lost )
Home ( 9 wins,1 draw,1 lost )
Away ( 7 wins,1 draw,1 lost )
OPP = Opposition,
FS = Final score.