| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 27-Aug-2021 | lose |  Internazionale | 1-3 | home |
| 22-Sep-2021 | draw |  Salernitana | 2-2 | away |
| 25-Sep-2021 | draw |  Genoa | 3-3 | away |
| 03-Oct-2021 | win | Spezia Calcio | 4-0 | home |
| 16-Oct-2021 | lose |  AC Milan | 3-2 | away |
| 24-Oct-2021 | win |  SS Lazio | 4-1 | home |
| 30-Oct-2021 | win |  Juventus | 2-1 | home |
| 07-Nov-2021 | draw |  Napoli | 1-1 | away |
| 22-Nov-2021 | win |  Empoli | 2-1 | home |
| 27-Nov-2021 | lose |  Sampdoria | 3-1 | away |
| 12-Dec-2021 | lose |  Atalanta | 1-2 | home |
| 22-Dec-2021 | draw |  Fiorentina | 1-1 | home |
| 06-Jan-2022 | win | Spezia Calcio | 1-2 | away |
| 16-Jan-2022 | win |  Sassuolo | 2-4 | away |
| 13-Feb-2022 | win |  Udinese | 4-0 | home |
| 19-Feb-2022 | draw |  AS Roma | 2-2 | away |
| 27-Feb-2022 | win | Venezia | 3-1 | home |
| 06-Mar-2022 | draw | Fiorentina | 1-1 | away |
| 04-Apr-2022 | win | Genoa | 1-0 | home |
| 18-Apr-2022 | win | Atalanta | 1-2 | away |
| 30-Apr-2022 | win |  Cagliari | 1-2 | away |
| 08-May-2022 | lose | AC Milan | 1-3 | home |
| 21-May-2022 | draw | SS Lazio | 3-3 | away |
Overall ( 11 wins,7 draw,5 lost )
Home ( 7 wins,1 draw,3 lost )
Away ( 4 wins,6 draw,2 lost )
OPP = Opposition,
FS = Final score.