| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Rui Patricio | 38 | 38 | - | - | - | - |
Tammy Abraham | 37 | 36 | 1 | 1 | 13 | 17 |
Rick Karsdorp | 36 | 32 | 4 | 4 | 10 | - |
Jordan Veretout | 36 | 26 | 10 | 10 | 18 | 4 |
Roger Ibanez | 34 | 32 | 3 | 2 | - | 3 |
Bryan Cristante | 34 | 29 | 5 | 5 | 2 | 2 |
Gianluca Mancini | 33 | 33 | 1 | - | 5 | - |
Henrikh Mkhitaryan | 31 | 29 | 3 | 2 | 10 | 5 |
Lorenzo Pellegrini | 28 | 27 | 1 | 1 | 11 | 9 |
Nicolo Zaniolo | 28 | 23 | 7 | 5 | 13 | 2 |
Eldor Shomurodov | 28 | 5 | 32 | 23 | 4 | 3 |
Chris Smalling | 27 | 23 | 7 | 4 | 2 | 3 |
Stephan El Shaaraway | 27 | 8 | 23 | 19 | 7 | 3 |
Matias Vina | 26 | 18 | 16 | 8 | 9 | - |
Carles Perez | 19 | 3 | 32 | 16 | 4 | 1 |
Marash Kumbulla | 18 | 13 | 22 | 5 | 5 | - |
Felix Afena-Gyan | 17 | 6 | 19 | 11 | 6 | 2 |
Nicola Zalewski | 16 | 9 | 25 | 7 | 9 | - |
Sergio Oliveira | 14 | 13 | 2 | 1 | 11 | 2 |
Edoardo Bove | 11 | - | 32 | 11 | - | 1 |
Ainsley Maitland-Niles | 8 | 7 | 11 | 1 | 6 | - |
Riccardo Calafiori | 6 | 2 | 16 | 4 | 2 | - |
Borja Mayoral | 5 | 1 | 15 | 4 | 1 | - |
Amadou Diawara | 4 | 2 | 27 | 2 | 1 | - |
Leonardo Spinazzola | 3 | 2 | 5 | 1 | 2 | - |
Cristian Volpato | 3 | - | 8 | 3 | - | 1 |
Ebrima Darboe | 1 | 1 | 21 | - | 1 | - |
Dimitrios Keramitsis | 1 | - | 7 | 1 | - | - |
Bryan Reynolds | 1 | - | 11 | 1 | - | - |
Daniel Fuzato | - | - | 35 | - | - | - |
Gonzalo Villar | - | - | 12 | - | - | - |
Davide Mastrantonio | - | - | 3 | - | - | - |
Pietro Boer | - | - | 23 | - | - | - |
Jan Oliveras | - | - | 1 | - | - | - |
Maissa Ndiaye | - | - | 2 | - | - | - |
Filippo Tripi | - | - | 6 | - | - | - |
Flippo Missori | - | - | 2 | - | - | - | 570 | 418 | 450 | 152 | 152 | 58 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .