| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 21-Aug-2021 | lose |  SC Freiburg | 2-1 | away |
| 11-Sep-2021 | win |  Bayer Leverkusen | 3-4 | away |
| 25-Sep-2021 | lose |  Borussia M'gladbach | 1-0 | away |
| 06-Nov-2021 | lose |  RB Leipzig | 2-1 | away |
| 27-Nov-2021 | win |  VfL Wolfsburg | 1-3 | away |
| 11-Dec-2021 | draw |  VfL Bochum | 1-1 | away |
| 08-Jan-2022 | win |  Eintracht Frankfurt | 2-3 | away |
| 06-Feb-2022 | lose | Bayer Leverkusen | 2-5 | home |
| 02-Apr-2022 | lose | RB Leipzig | 1-4 | home |
| 23-Apr-2022 | lose |  Bayern Munich | 3-1 | away |
| 30-Apr-2022 | lose | VfL Bochum | 3-4 | home |
| 14-May-2022 | win |  Hertha BSC | 2-1 | home |
Overall ( 4 wins,1 draw,7 lost )
Home ( 1 wins,0 draw,3 lost )
Away ( 3 wins,1 draw,4 lost )
OPP = Opposition,
FS = Final score.