| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 23-Aug-2021 | draw |  Spezia Calcio | 2-2 | home |
| 29-Aug-2021 | lose |  AC Milan | 4-1 | away |
| 19-Sep-2021 | draw |  SS Lazio | 2-2 | away |
| 22-Sep-2021 | lose |  Empoli | 0-2 | home |
| 26-Sep-2021 | lose |  Napoli | 2-0 | away |
| 24-Oct-2021 | lose |  Fiorentina | 3-0 | away |
| 01-Nov-2021 | lose |  Bologna | 2-0 | away |
| 06-Nov-2021 | lose |  Atalanta | 1-2 | home |
| 21-Nov-2021 | draw |  Sassuolo | 2-2 | away |
| 06-Dec-2021 | draw |  Torino | 1-1 | home |
| 12-Dec-2021 | lose |  Internazionale | 4-0 | away |
| 18-Dec-2021 | lose |  Udinese | 0-4 | home |
| 21-Dec-2021 | lose |  Juventus | 2-0 | away |
| 06-Jan-2022 | win |  Sampdoria | 1-2 | away |
| 11-Jan-2022 | win | Bologna | 2-1 | home |
| 16-Jan-2022 | lose |  AS Roma | 1-0 | away |
| 13-Feb-2022 | draw | Empoli | 1-1 | away |
| 05-Mar-2022 | lose | SS Lazio | 0-3 | home |
| 12-Mar-2022 | lose | Spezia Calcio | 2-0 | away |
| 19-Mar-2022 | lose | AC Milan | 0-1 | home |
| 24-Apr-2022 | lose |  Genoa | 1-0 | away |
| 30-Apr-2022 | lose | Hellas Verona | 1-2 | home |
| 08-May-2022 | draw | Salernitana | 1-1 | away |
| 15-May-2022 | lose | Internazionale | 1-3 | home |
Overall ( 2 wins,6 draw,16 lost )
Home ( 1 wins,2 draw,7 lost )
Away ( 1 wins,4 draw,9 lost )
OPP = Opposition,
FS = Final score.