| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 21-Aug-2021 | win |  Empoli | 1-3 | away |
| 28-Aug-2021 | win |  Spezia Calcio | 6-1 | home |
| 12-Sep-2021 | lose |  AC Milan | 2-0 | away |
| 23-Sep-2021 | draw |  Torino | 1-1 | away |
| 03-Oct-2021 | lose |  Bologna | 3-0 | away |
| 16-Oct-2021 | win |  Internazionale | 3-1 | home |
| 24-Oct-2021 | lose | Hellas Verona | 4-1 | away |
| 20-Nov-2021 | lose |  Juventus | 0-2 | home |
| 28-Nov-2021 | lose |  Napoli | 4-0 | away |
| 02-Dec-2021 | draw |  Udinese | 4-4 | home |
| 06-Jan-2022 | draw | Empoli | 3-3 | home |
| 09-Jan-2022 | lose | Internazionale | 2-1 | away |
| 20-Feb-2022 | draw | Udinese | 1-1 | away |
| 27-Feb-2022 | lose | Napoli | 1-2 | home |
| 20-Mar-2022 | lose |  AS Roma | 3-0 | away |
| 16-Apr-2022 | draw | Torino | 1-1 | home |
| 30-Apr-2022 | win | Spezia Calcio | 3-4 | away |
| 16-May-2022 | draw | Juventus | 2-2 | away |
| 21-May-2022 | draw | Hellas Verona | 3-3 | home |
Overall ( 4 wins,7 draw,8 lost )
Home ( 2 wins,4 draw,2 lost )
Away ( 2 wins,3 draw,6 lost )
OPP = Opposition,
FS = Final score.