| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Nick Rimando | Real Salt Lake | United States | 5 | |
| 2 | Matthew Pickens | Colorado Rapids | United States | 4 | |
| 3 | Faryd Mondragon | Philadelphia Union | Colombia | 3 | |
| 4 | Frank Rost | New York Red Bulls | Germany | 3 | |
| 5 | Kasey Keller | Seattle Sounders | United States | 3 | |
| 6 | Jimmy Nielsen | Sporting Kansas City | Denmark | 2 | |
| 7 | Kevin Hartman | FC Dallas | United States | 2 | |
| 8 | Tally Hall | Houston Dynamo | United States | 2 | |
| 9 | Josh Saunders | Los Angeles Galaxy | United States | 2 | |
| 10 | Will Hesmer | Columbus Crew | United States | 1 |
GC = Goals conceded