| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Borja Iglesias | 35 | 29 | 6 | 6 | 22 | 15 |
Guido Rodriguez | 34 | 33 | 2 | 1 | 7 | 1 |
William Carvalho | 33 | 31 | 2 | 2 | 17 | 3 |
Luiz Henrique | 33 | 21 | 14 | 12 | 18 | 1 |
German Pezzella | 31 | 29 | 4 | 2 | 4 | - |
Sergio Canales | 31 | 28 | 3 | 3 | 13 | 4 |
Rodri | 30 | 19 | 18 | 11 | 15 | 2 |
Willian Jose | 28 | 6 | 29 | 22 | 4 | 2 |
Rui Silva | 26 | 26 | 11 | - | - | - |
Andres Guardado | 26 | 16 | 19 | 10 | 10 | 1 |
Aitor Ruibal | 26 | 15 | 21 | 11 | 6 | - |
Edgar Gonzalez | 25 | 18 | 17 | 7 | 1 | - |
Luiz Felipe | 23 | 22 | 4 | 1 | 3 | - |
Youssouf Sabaly | 23 | 19 | 8 | 4 | 5 | 1 |
Juanmi | 22 | 9 | 16 | 13 | 6 | 4 |
Joaquin | 22 | 2 | 31 | 20 | 2 | - |
Juan Miranda | 21 | 16 | 21 | 5 | 5 | 3 |
Ayoze Perez | 19 | 17 | 2 | 2 | 12 | 3 |
Alex Moreno | 15 | 15 | 1 | - | - | - |
Nabil Fekir | 15 | 12 | 3 | 3 | 6 | 2 |
Abner | 13 | 7 | 14 | 6 | 4 | - |
Claudio Bravo | 12 | 12 | 21 | - | - | - |
Paul Akouokou | 12 | 3 | 28 | 9 | 1 | - |
Victor Ruiz | 10 | 5 | 19 | 5 | - | - |
Martin Montoya | 6 | 6 | 27 | - | 3 | - |
Juan Cruz | 6 | 1 | 17 | 5 | 1 | 1 |
Loren Moron | 2 | - | 17 | 2 | - | - |
Robert Gonzalez | 2 | - | 3 | 2 | - | - |
Felix Marti | 1 | 1 | 1 | - | - | - |
Fran Delgado | 1 | - | 4 | 1 | - | - |
Felix Garreta | - | - | 2 | - | - | - |
Ricardo Visus | - | - | 2 | - | - | - |
Jose Alonso Lara | - | - | 1 | - | - | - |
Fran Vieites | - | - | 1 | - | - | - |
Dani Martin | - | - | 29 | - | - | - | 583 | 418 | 418 | 165 | 165 | 43 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .