| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Felipe Anderson | 38 | 33 | 5 | 5 | 17 | 6 |
Sergej Milinkovic-Savic | 37 | 36 | 1 | 1 | 9 | 11 |
Lucas Leiva | 35 | 19 | 17 | 16 | 14 | - |
Luis Alberto | 34 | 27 | 8 | 7 | 16 | 5 |
Adam Marusic | 33 | 30 | 5 | 3 | 3 | 1 |
Pedro Rodriguez | 32 | 25 | 7 | 7 | 15 | 9 |
Danilo Cataldi | 32 | 19 | 15 | 13 | 18 | 1 |
Ciro Immobile | 31 | 31 | - | - | 6 | 27 |
Luiz Felipe | 31 | 28 | 6 | 3 | 5 | - |
Manuel Lazzari | 31 | 16 | 18 | 15 | 7 | 3 |
Franciesco Acerbi | 30 | 29 | 1 | 1 | 1 | 4 |
Elseid Hysaj | 29 | 24 | 12 | 5 | 9 | 1 |
Mattia Zaccagni | 29 | 21 | 8 | 8 | 10 | 4 |
Toma Basic | 29 | 9 | 27 | 20 | 7 | - |
Patric | 24 | 19 | 17 | 5 | 7 | 1 |
Thomas Strakosha | 23 | 23 | 14 | - | - | - |
Pepe Reina | 15 | 15 | 23 | - | - | - |
Vedat Muriqi | 11 | 1 | 22 | 10 | 1 | - |
Raul Moro | 11 | 1 | 34 | 10 | 1 | - |
Stefan Radu | 10 | 6 | 27 | 4 | 3 | - |
Jean Daniel Akpa Akpro | 10 | 4 | 26 | 6 | 4 | - |
Luka Romero | 8 | - | 30 | 8 | - | - |
Andre Anderson | 4 | - | 16 | 4 | - | - |
Jovane Cabral | 3 | 2 | 13 | 1 | 2 | 1 |
Denis Vavro | 1 | - | 12 | 1 | - | - |
Gonzalo Escalante | 1 | - | 16 | 1 | - | - |
Dimitrije Kamenovic | 1 | - | 14 | 1 | - | - |
Alessio Furlanetto | - | - | 1 | - | - | - |
Romano Floriani | - | - | 5 | - | - | - |
Marco Bertini | - | - | 3 | - | - | - |
Marius Adamonis | - | - | 36 | - | - | - |
Felipe Caicedo | - | - | 1 | - | - | - |
Jony | - | - | 1 | - | - | - | 573 | 418 | 441 | 155 | 155 | 74 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .