| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Rubinho | 37 | 37 | 1 | - | 1 | - |
Domenico Criscito | 35 | 35 | - | - | 4 | 3 |
Guiseppe Sculli | 35 | 28 | 8 | 7 | 18 | 8 |
Matteo Ferrari | 33 | 33 | 1 | - | 1 | - |
Ivan Juric | 33 | 32 | 1 | 1 | 3 | - |
Salvatore Bocchetti | 32 | 28 | 7 | 4 | 6 | - |
Diego Milito | 31 | 30 | 1 | 1 | 3 | 24 |
Marco Rossi | 30 | 23 | 11 | 7 | 9 | - |
Giuseppe Biava | 29 | 28 | 3 | 1 | 3 | 2 |
Raffaele Palladino | 28 | 18 | 10 | 10 | 8 | 3 |
Thiago Motta | 27 | 25 | 2 | 2 | 3 | 6 |
Giandomencio Mesto | 27 | 22 | 7 | 5 | 13 | 1 |
Omar Milanetto | 26 | 18 | 9 | 8 | 5 | - |
Bosko Jankovic | 25 | 15 | 16 | 10 | 9 | 3 |
Anthony Vanden Borre | 25 | 8 | 22 | 17 | 5 | - |
Sokratis Papastathopoulos | 21 | 13 | 18 | 8 | 3 | 2 |
Ruben Olivera | 18 | 7 | 19 | 11 | 4 | 4 |
Francesco Modesto | 14 | 9 | 15 | 5 | 4 | - |
Andrea Gasbarroni | 9 | 6 | 4 | 3 | 6 | - |
Alessandro Potenza | 5 | 2 | 4 | 3 | 1 | - |
Alessio Scarpi | 2 | 1 | 17 | 1 | - | - |
Davide Brivio | 1 | - | 4 | 1 | - | - |
Davide Di Gennaro | 1 | - | 1 | 1 | - | - |
Marcel Roman | 1 | - | 4 | 1 | - | - |
Stephan El Shaaraway | 1 | - | 5 | 1 | - | - |
Andrea Signorini | 1 | - | 2 | 1 | - | - |
Matteo D'Alessandro | - | - | 3 | - | - | - |
Luciano Figueroa | - | - | 1 | - | - | - |
Dejan Lazarevic | - | - | 1 | - | - | - |
Nicholas Constantini | - | - | 1 | - | - | - |
Carlo Polli | - | - | 1 | - | - | - |
Eugenio Lamanna | - | - | 7 | - | - | - |
Louise Parfait | - | - | 2 | - | - | - | 527 | 418 | 208 | 109 | 109 | 56 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .