| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 15-Aug-2021 | win |  RB Leipzig | 1-0 | home |
| 28-Aug-2021 | win |  SpVgg Greuther Furth | 3-0 | home |
| 11-Sep-2021 | win |  TSG 1899 Hoffenheim | 0-2 | away |
| 03-Oct-2021 | lose | 1. FC Union Berlin | 1-2 | home |
| 22-Oct-2021 | win |  FC Augsburg | 4-1 | home |
| 30-Oct-2021 | win | Arminia Bielefeld | 1-2 | away |
| 21-Nov-2021 | draw |  1. FC Koln | 1-1 | home |
| 04-Dec-2021 | win |  VfL Wolfsburg | 3-0 | home |
| 11-Dec-2021 | lose |  Bayern Munich | 2-1 | away |
| 14-Dec-2021 | win |  Hertha BSC | 4-0 | home |
| 15-Jan-2022 | win | VfL Bochum | 1-0 | home |
| 05-Feb-2022 | win | TSG 1899 Hoffenheim | 2-0 | home |
| 12-Feb-2022 | draw |  SC Freiburg | 1-1 | away |
| 19-Mar-2022 | win | Arminia Bielefeld | 4-0 | home |
| 09-Apr-2022 | lose | 1. FC Koln | 3-2 | away |
| 30-Apr-2022 | win | Bayern Munich | 3-1 | home |
| 07-May-2022 | win | Hertha BSC | 1-2 | away |
| 14-May-2022 | draw |  Eintracht Frankfurt | 2-2 | home |
Overall ( 12 wins,3 draw,3 lost )
Home ( 9 wins,2 draw,1 lost )
Away ( 3 wins,1 draw,2 lost )
OPP = Opposition,
FS = Final score.