| 4 | Pedro Goncalves | Group Stage | UEFA Champions League 21/22 |
| 4 | Nani | Group Stage | UEFA Champions League 14/15 |
| 4 | Liedson | Group Stage | UEFA Champions League 07/08 |
| 3 | Paulinho | Group Stage | UEFA Champions League 21/22 |
| 3 | Sa Pinto | First Group Stage | UEFA Champions League 00/01 |
| 2 | Arthur Gomes | Group Stage | UEFA Champions League 22/23 |
| 2 | Marcus Edwards | Group Stage | UEFA Champions League 22/23 |
| 2 | Francisco Trincao | Group Stage | UEFA Champions League 22/23 |
| 2 | Sebastian Coates | Group Stage | UEFA Champions League 21/22 |
| 2 | Pablo Sarabia | Group Stage | UEFA Champions League 21/22 |
| 2 | Bruno Cesar | Group Stage | UEFA Champions League 17/18 |
| 2 | Bas Dost | Group Stage | UEFA Champions League 17/18 |
| 2 | Bruno Cesar | Group Stage | UEFA Champions League 16/17 |
| 2 | Islam Slimani | Group Stage | UEFA Champions League 14/15 |
| 2 | Adrien Silva | Group Stage | UEFA Champions League 14/15 |
| 2 | Derlei | Group Stage | UEFA Champions League 08/09 |
| 2 | Liedson | Group Stage | UEFA Champions League 08/09 |
| 2 | Oceano da Cruz | Group Stage | UEFA Champions League 97/98 |
| 2 | Mustafa Hadji | Group Stage | UEFA Champions League 97/98 |
| 2 | Leandro Machado | Group Stage | UEFA Champions League 97/98 |
| 2 | Anderson Polga | Group Stage | UEFA Champions League 07/08 |
| 2 | Andre Cruz | First Group Stage | UEFA Champions League 00/01 |
| 1 | Paulinho | Group Stage | UEFA Champions League 22/23 |
| 1 | Nuno Santos | Group Stage | UEFA Champions League 22/23 |
| 1 | Tabata | Group Stage | UEFA Champions League 21/22 |
| 1 | Pedro Porro | Group Stage | UEFA Champions League 21/22 |
| 1 | Nuno Santos | Group Stage | UEFA Champions League 21/22 |
| 1 | Seydou Doumbia | Group Stage | UEFA Champions League 17/18 |
| 1 | Bruno Fernandes | Group Stage | UEFA Champions League 17/18 |
| 1 | Gelson Martins | Group Stage | UEFA Champions League 17/18 |
| 1 | Adrien Silva | Group Stage | UEFA Champions League 16/17 |
| 1 | Bas Dost | Group Stage | UEFA Champions League 16/17 |
| 1 | Bryan Ruiz | Group Stage | UEFA Champions League 16/17 |
| 1 | Jonathan Silva | Group Stage | UEFA Champions League 14/15 |
| 1 | Mahamadou-Naby Sarr | Group Stage | UEFA Champions League 14/15 |
| 1 | Jefferson | Group Stage | UEFA Champions League 14/15 |
| 1 | Carlos Mane | Group Stage | UEFA Champions League 14/15 |
| 1 | Tonel | Group Stage | UEFA Champions League 08/09 |
| 1 | Yannick Djalo | Group Stage | UEFA Champions League 08/09 |
| 1 | Joao Moutinho | Round of 16 | UEFA Champions League 08/09 |
| 1 | Miguel Veloso | Group Stage | UEFA Champions League 08/09 |
| 1 | Luis Miguel | Group Stage | UEFA Champions League 97/98 |
| 1 | Cesar Ramirez | Group Stage | UEFA Champions League 97/98 |
| 1 | Bruno Gimenez | Group Stage | UEFA Champions League 97/98 |
| 1 | Abel | Group Stage | UEFA Champions League 07/08 |
| 1 | Joao Moutinho | Group Stage | UEFA Champions League 07/08 |
| 1 | Tonel | Group Stage | UEFA Champions League 07/08 |
| 1 | Carlos Bueno | Group Stage | UEFA Champions League 06/07 |
| 1 | Marco Caneira | Group Stage | UEFA Champions League 06/07 |
| 1 | Nani | Group Stage | UEFA Champions League 06/07 |
