| MD | Players | Clubs | Nationality | DOB | A(D) |
|---|---|---|---|---|---|
| 24-Aug-2005 |  Reece Brown | Manchester United | England | 01-Nov-1991 | 13(297) |
| 09-Aug-2005 | Giuseppe Rossi | Manchester United | Italy | 01-Feb-1987 | 18(190) |
| 09-Aug-2005 | Wayne Rooney | Manchester United | England | 24-Oct-1985 | 19(289) |
| 24-Aug-2005 | Philip Bardsley | Manchester United | Scotland | 28-Jun-1985 | 20(57) |
| 09-Aug-2005 | Cristiano Ronaldo | Manchester United | Portugal | 05-Feb-1985 | 20(185) |
| 09-Aug-2005 |  Peter Mate | Debreceni VSC | Hungary | 02-Dec-1984 | 20(250) |
| 09-Aug-2005 | Darren Fletcher | Manchester United | Scotland | 01-Feb-1984 | 21(190) |
| 09-Aug-2005 | Aco Stojkov | Debreceni VSC | Macedonia | 29-Apr-1983 | 22(103) |
| 09-Aug-2005 | John O'Shea | Manchester United | Republic of Ireland | 30-Apr-1981 | 24(101) |
| 09-Aug-2005 | Ji Sung Park | Manchester United | South Korea | 25-Feb-1981 | 24(165) |
| 24-Aug-2005 | Liam Miller | Manchester United | Republic of Ireland | 13-Feb-1981 | 24(192) |
| 09-Aug-2005 | Alan Smith | Manchester United | England | 28-Oct-1980 | 24(285) |
| 09-Aug-2005 | Zoltan Kiss | Debreceni VSC | Hungary | 18-Aug-1980 | 24(356) |
| 09-Aug-2005 | Ibrahim Sidibe | Debreceni VSC | Senegal | 10-Aug-1980 | 24(364) |
| 09-Aug-2005 | Csaba Bernath | Debreceni VSC | Hungary | 26-Mar-1979 | 26(137) |
| 09-Aug-2005 | Rio Ferdinand | Manchester United | England | 07-Nov-1978 | 26(276) |
| 24-Aug-2005 | Gabriel Heinze | Manchester United | Argentina | 19-Mar-1978 | 27(158) |
| 09-Aug-2005 | Adam Komlosi | Debreceni VSC | Hungary | 06-Nov-1977 | 27(276) |
| 09-Aug-2005 | Mikael Silvestre | Manchester United | France | 09-Aug-1977 | 28(0) |
| 09-Aug-2005 | Balazs Nikolov | Debreceni VSC | Hungary | 04-Jul-1977 | 28(36) |
| 09-Aug-2005 | Ruud van Nistelrooy | Manchester United | Netherlands | 01-Jul-1976 | 29(39) |
| 09-Aug-2005 | Norbert Csernyanski | Debreceni VSC | Hungary | 01-Feb-1976 | 29(190) |
| 09-Aug-2005 | Gary Neville | Manchester United | England | 18-Feb-1975 | 30(173) |
| 09-Aug-2005 | Paul Scholes | Manchester United | England | 16-Nov-1974 | 30(267) |
| 24-Aug-2005 | Ryan Giggs | Manchester United | Wales | 29-Nov-1973 | 31(268) |
| 09-Aug-2005 | Tibor Dombi | Debreceni VSC | Hungary | 11-Nov-1973 | 31(271) |
| 09-Aug-2005 | Zsombor Kerekes | Debreceni VSC | Serbia | 13-Sep-1973 | 31(331) |
| 09-Aug-2005 | Roy Keane | Manchester United | Republic of Ireland | 10-Aug-1971 | 33(365) |
| 09-Aug-2005 | Edwin van der Sar | Manchester United | Netherlands | 29-Oct-1970 | 34(285) |
MD = Match date,
DOB = Date Of Birth,
A(D) = Age(Days).