| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Esteban | UD Almeria | Spain | 71 | |
| 2 | Andres Fernandez | Osasuna | Spain | 63 | |
| 3 | Claudio Bravo | Real Sociedad | Chile | 55 | |
| 4 | Yoel Rodriguez | Celta Vigo | Spain | 54 | |
| 5 | Diego Marino | Real Valladolid | Spain | 48 | |
| 6 | Kiko Casilla | Espanyol | Spain | 48 | |
| 7 | Beto | Sevilla | Portugal | 48 | |
| 8 | Willy Caballero | Malaga | Argentina | 46 | |
| 9 | Ruben | Rayo Vallecano | Spain | 46 | |
| 10 | Roberto | Granada CF | Spain | 44 | |
| 11 | Keylor Navas | Levante | Costa Rica | 44 | |
| 12 | Sergio Asenjo | Villarreal | Spain | 43 | |
| 13 | Miguel Angel Moya | Getafe | Spain | 41 | |
| 14 | Diego Lopez | Real Madrid | Spain | 37 | |
| 15 | Manu Herrera | Elche CF | Spain | 37 | |
| 16 | Diego Alves | Valencia | Brazil | 33 | |
| 17 | Gorka Iraizoz | Athletic Bilbao | Spain | 32 | |
| 18 | Antonio Adan | Real Betis | Spain | 32 | |
| 19 | Guillermo Sara | Real Betis | Argentina | 31 | |
| 20 | Thibaut Courtois | Atletico Madrid | Belgium | 27 |
GC = Goals conceded