| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Dudu Aouate | RCD Mallorca | Israel | 65 | |
| 2 | Daniel Aranzubia | Deportivo La Coruna | Spain | 62 | |
| 3 | Gorka Iraizoz | Athletic Bilbao | Spain | 61 | |
| 4 | Roberto Gago | Real Zaragoza | Spain | 51 | |
| 5 | Ruben | Rayo Vallecano | Spain | 50 | |
| 6 | Javier Varas | Celta Vigo | Spain | 49 | |
| 7 | Gustavo Munua | Levante | Uruguay | 48 | |
| 8 | Willy Caballero | Malaga | Argentina | 47 | |
| 9 | Miguel Angel Moya | Getafe | Spain | 44 | |
| 10 | Andres Fernandez | Osasuna | Spain | 42 | |
| 11 | Claudio Bravo | Real Sociedad | Chile | 41 | |
| 12 | Adrian | Real Betis | Spain | 40 | |
| 13 | Tono | Granada CF | Spain | 38 | |
| 14 | Dani Hernandez | Real Valladolid | Venezuela | 37 | |
| 15 | Diego Alves | Valencia | Brazil | 35 | |
| 16 | Diego Lopez | Sevilla | Spain | 34 | |
| 17 | Victor Valdes | Barcelona | Spain | 34 | |
| 18 | Thibaut Courtois | Atletico Madrid | Belgium | 30 | |
| 19 | Cristian Alvarez | Espanyol | Argentina | 28 | |
| 20 | Kiko Casilla | Espanyol | Spain | 25 |
GC = Goals conceded