| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Martin Dubravka | MSK Zilina | Slovakia | 19 | |
| 2 | Manuel Neuer | FC Schalke 04 | Germany | 15 | |
| 3 | Dimitar Ivankov | Bursaspor | Bulgaria | 15 | |
| 4 | Julio Cesar | Internazionale | Brazil | 15 | |
| 5 | Hugo Lloris | Olympique Lyonnais | France | 14 | |
| 6 | Andrei Pyatov | Shakhtar Donetsk | Ukraine | 14 | |
| 7 | Heurelho Gomes | Tottenham Hotspur | Brazil | 14 | |
| 8 | Alexandros Tzorvas | Panathinaikos | Greece | 13 | |
| 9 | Olivier Sorin | AJ Auxerre | France | 12 | |
| 10 | Roberto Gago | Benfica | Spain | 12 | |
| 11 | Andriy Dykan | Spartak Moscow | Ukraine | 11 | |
| 12 | Vladimir Stojkovic | Partizan Belgrade | Serbia | 11 | |
| 13 | Franco Costanzo | FC Basel | Argentina | 11 | |
| 14 | Maarten Stekelenburg | AFC Ajax | Netherlands | 10 | |
| 15 | Tim Wiese | Werder Bremen | Germany | 10 | |
| 16 | Vincent Enyeama | Hapoel Tel Aviv | Nigeria | 10 | |
| 17 | Felipe | Sporting Braga | Brazil | 9 | |
| 18 | Victor Valdes | Barcelona | Spain | 9 | |
| 19 | Nikolay Mihaylov | FC Twente | Bulgaria | 8 | |
| 20 | Johan Wiland | FC Copenhagen | Sweden | 8 |
GC = Goals conceded