| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Sergio Aragoneses | CD Tenerife | Spain | 74 | |
| 2 | Renan Brito Soares | Xerez CD | Brazil | 60 | |
| 3 | Diego Lopez | Villarreal | Spain | 57 | |
| 4 | Gorka Iraizoz | Athletic Bilbao | Spain | 55 | |
| 5 | Diego Alves | UD Almeria | Brazil | 54 | |
| 6 | Gustavo Munua | Malaga | Uruguay | 48 | |
| 7 | Andres Palop | Sevilla | Spain | 47 | |
| 8 | Juan Pablo | Sporting Gijon | Spain | 46 | |
| 9 | Dudu Aouate | RCD Mallorca | Israel | 46 | |
| 10 | Daniel Aranzubia | Deportivo La Coruna | Spain | 45 | |
| 11 | Ricardo | Osasuna | Spain | 44 | |
| 12 | Carlos Kameni | Espanyol | Cameroon | 40 | |
| 13 | Justo Villar | Real Valladolid | Paraguay | 38 | |
| 14 | Iker Casillas | Real Madrid | Spain | 35 | |
| 15 | Fabio Coltorti | Racing Santander | Switzerland | 34 | |
| 16 | Juan Carrizo | Real Zaragoza | Argentina | 30 | |
| 17 | Cesar Sanchez | Valencia | Spain | 29 | |
| 18 | David de Gea | Atletico Madrid | Spain | 28 | |
| 19 | Victor Valdes | Barcelona | Spain | 27 | |
| 20 | Roberto Gago | Atletico Madrid | Spain | 26 |
GC = Goals conceded