| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Marten de Roon | 13 | 13 | - | - | - | - |
Ederson | 13 | 12 | 1 | 1 | 3 | 2 |
Matteo Ruggeri | 13 | 12 | 1 | 1 | 9 | - |
Giorgio Scalvini | 13 | 12 | 1 | 1 | 4 | - |
Teun Koopmeiners | 13 | 11 | 2 | 2 | 4 | 4 |
Ademola Lookman | 13 | 10 | 3 | 3 | 10 | 4 |
Charles de Ketelaere | 13 | 7 | 6 | 6 | 7 | 2 |
Berat Djimsiti | 12 | 11 | 2 | 1 | 1 | - |
Davide Zappacosta | 12 | 11 | 2 | 1 | 9 | - |
Sead Kolasinac | 11 | 9 | 2 | 2 | 2 | 1 |
Mario Pasalic | 10 | 6 | 7 | 4 | 4 | 2 |
Juan Musso | 8 | 8 | 5 | - | - | - |
Gianluca Scamacca | 8 | 4 | 4 | 4 | 3 | 4 |
Luis Muriel | 8 | 1 | 10 | 7 | 1 | 2 |
Emil Holm | 7 | 2 | 7 | 5 | 2 | - |
Rafael Toloi | 6 | 3 | 6 | 3 | 1 | - |
Aleksei Miranchuk | 6 | 2 | 8 | 4 | 2 | 1 |
Marco Carnesecchi | 5 | 5 | 8 | - | - | - |
Michel Ndary Adopo | 5 | - | 13 | 5 | - | - |
Hans Hateboer | 4 | 1 | 8 | 3 | - | - |
Mitchel Bakker | 4 | - | 11 | 4 | - | - |
Nadir Zortea | 3 | - | 10 | 3 | - | 1 |
Duvan Zapata | 2 | 2 | - | - | 2 | 1 |
Isak Hien | 2 | 1 | 1 | 1 | - | - |
Jose Luis Palomino | 2 | - | 6 | 2 | - | - |
El Bilal Toure | 1 | - | 2 | 1 | - | - |
Caleb Okoli | - | - | 2 | - | - | - |
Leonardo Mendicino | - | - | 1 | - | - | - |
Pietro Comi | - | - | 1 | - | - | - |
Matteo Colombo | - | - | 1 | - | - | - |
Francesco Rossi | - | - | 13 | - | - | - |
Tommaso Del Lungo | - | - | 1 | - | - | - |
Giovanni Bonfanti | - | - | 4 | - | - | - |
Moustapha Cisse | - | - | 2 | - | - | - |
Alessandro Cortinovis | - | - | 1 | - | - | - |
Marco Palestra | - | - | 1 | - | - | - | 207 | 143 | 153 | 64 | 64 | 24 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .