| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Henrikh Mkhitaryan | 18 | 17 | 1 | 1 | 11 | 2 |
Nicolo Barella | 18 | 16 | 2 | 2 | 7 | 1 |
Carlos Augusto | 18 | 5 | 13 | 13 | 1 | - |
Hakan Calhanoglu | 17 | 17 | 1 | - | 10 | 6 |
Marcus Thuram | 17 | 17 | - | - | 12 | 7 |
Yann Sommer | 17 | 17 | - | - | - | - |
Lautaro Martinez | 17 | 16 | 1 | 1 | 6 | 18 |
Denzel Dumfries | 16 | 14 | 3 | 2 | 9 | 3 |
Federico Dimarco | 15 | 14 | 3 | 1 | 13 | 2 |
Matteo Darmian | 15 | 11 | 7 | 4 | 4 | - |
Davide Frattesi | 15 | 2 | 14 | 13 | 2 | 3 |
Stefan de Vrij | 14 | 10 | 7 | 4 | 1 | 1 |
Franciesco Acerbi | 13 | 13 | - | - | - | 1 |
Alessandro Bastoni | 12 | 12 | 4 | - | 5 | - |
Marko Arnautovic | 12 | 1 | 11 | 11 | 1 | 2 |
Kristjan Asllani | 10 | 1 | 16 | 9 | 1 | - |
Benjamin Pavard | 9 | 8 | 5 | 1 | 4 | - |
Alexis Sanchez | 9 | 2 | 12 | 7 | 1 | - |
Juan Cuadrado | 7 | - | 8 | 7 | - | - |
Yann Aurel Bisseck | 6 | 3 | 15 | 3 | 1 | - |
Davy Klaassen | 6 | 1 | 15 | 5 | 1 | - |
Stefano Sensi | 2 | - | 12 | 2 | - | - |
Tajon Buchanan | 2 | - | 2 | 2 | - | - |
Emil Audero | 1 | 1 | 16 | - | - | - |
Ebenezer Akinsanmiro | 1 | - | 1 | 1 | - | - |
Lucien Agoume | 1 | - | 14 | 1 | - | - |
Joaquin Correa | - | - | 1 | - | - | - |
Raffaele di Gennaro | - | - | 17 | - | - | - |
Amadou Sarr | - | - | 6 | - | - | - |
Tommaso Guercio | - | - | 1 | - | - | - |
Aleksandar Stankovic | - | - | 6 | - | - | - |
Giacomo Stabile | - | - | 5 | - | - | - |
Matteo Motta | - | - | 1 | - | - | - |
Issiaka Kamate | - | - | 2 | - | - | - |
Alessandro Calligaris | - | - | 2 | - | - | - | 288 | 198 | 224 | 90 | 90 | 46 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .