| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Marten de Roon | 35 | 34 | 1 | 1 | 3 | 3 |
Ederson | 35 | 25 | 11 | 10 | 15 | 1 |
Joakim Maehle | 34 | 25 | 11 | 9 | 12 | 3 |
Teun Koopmeiners | 33 | 32 | 1 | 1 | 3 | 10 |
Rafael Toloi | 32 | 32 | 1 | - | 7 | 2 |
Giorgio Scalvini | 32 | 29 | 7 | 3 | 14 | 2 |
Mario Pasalic | 32 | 24 | 10 | 8 | 23 | 5 |
Rasmus Hojlund | 32 | 20 | 15 | 12 | 15 | 9 |
Ademola Lookman | 31 | 20 | 12 | 11 | 17 | 13 |
Luis Muriel | 29 | 10 | 21 | 19 | 9 | 3 |
Merih Demiral | 28 | 14 | 20 | 14 | 2 | 1 |
Duvan Zapata | 25 | 16 | 9 | 9 | 11 | 2 |
Juan Musso | 24 | 24 | 10 | - | 1 | - |
Berat Djimsiti | 24 | 20 | 9 | 4 | 4 | - |
Jeremie Boga | 23 | 5 | 28 | 18 | 5 | 2 |
Davide Zappacosta | 21 | 18 | 4 | 3 | 9 | 4 |
Hans Hateboer | 17 | 17 | 4 | - | 6 | 1 |
Caleb Okoli | 17 | 9 | 27 | 8 | 1 | - |
Marco Sportiello | 15 | 14 | 23 | 1 | 1 | - |
Brandon Soppy | 15 | 8 | 25 | 7 | 7 | - |
Matteo Ruggeri | 15 | 8 | 20 | 7 | 1 | - |
Jose Luis Palomino | 15 | 8 | 9 | 7 | 3 | 1 |
Ruslan Malinovskiy | 15 | 5 | 11 | 10 | 5 | 1 |
Nadir Zortea | 9 | 1 | 18 | 8 | 1 | 1 |
Lucas Vorlicky | 3 | - | 8 | 3 | - | - |
Francesco Rossi | 1 | - | 36 | 1 | - | - |
Tommaso de Nipoti | 1 | - | 3 | 1 | - | - |
Matteo Colombo | - | - | 4 | - | - | - |
Leonardo Mendicino | - | - | 4 | - | - | - |
Alessandro Falleni | - | - | 1 | - | - | - |
Iacopo Regonesi | - | - | 1 | - | - | - |
Endri Muhameti | - | - | 3 | - | - | - |
Mannah Chiwisa | - | - | 2 | - | - | - |
Lorenzo Bernasconi | - | - | 8 | - | - | - |
Marco Palestra | - | - | 2 | - | - | - |
Tomasso Bertini | - | - | 6 | - | - | - |
Tommaso Del Lungo | - | - | 1 | - | - | - | 593 | 418 | 386 | 175 | 175 | 64 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .