| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Matteo Politano | 7 | 7 | - | - | 6 | 2 |
Nikola Maksimovic | 7 | 7 | - | - | 1 | - |
Giovanni Di Lorenzo | 7 | 6 | 1 | 1 | - | - |
Lorenzo Insigne | 7 | 4 | 3 | 3 | 1 | - |
Fabian | 7 | 4 | 3 | 3 | 1 | 1 |
Kalidou Koulibaly | 6 | 6 | - | - | - | - |
Tiemoue Bakayoko | 6 | 4 | 3 | 2 | - | - |
Dries Mertens | 6 | 3 | 3 | 3 | 1 | 1 |
Alex Meret | 5 | 5 | 2 | - | - | - |
Stanislav Lobotka | 5 | 4 | 3 | 1 | 4 | - |
Elif Elmas | 5 | 4 | 2 | 1 | 3 | - |
Piotr Zielinski | 5 | 3 | 3 | 2 | 2 | 1 |
Andrea Petagna | 5 | 3 | 2 | 2 | 3 | - |
Diego Demme | 5 | 3 | 2 | 2 | 2 | 1 |
Mario Rui | 5 | 3 | 4 | 2 | 1 | - |
Hirving Lozano | 5 | 1 | 4 | 4 | 1 | 1 |
Faouzi Ghoulam | 4 | 2 | 4 | 2 | 1 | - |
Victor Osimhen | 3 | 2 | 1 | 1 | 1 | - |
Amir Rrahmani | 2 | 2 | 3 | - | - | - |
Elseid Hysaj | 2 | 2 | 1 | - | 1 | - |
David Ospina | 2 | 2 | 3 | - | - | - |
Davide Costanzo | - | - | 2 | - | - | - |
Kostas Manolas | - | - | 5 | - | - | - |
Nikita Contini | - | - | 7 | - | - | - |
Hubert Dawid Idasiak | - | - | 2 | - | - | - |
Valerio Labriola | - | - | 2 | - | - | - |
Karim Zedadka | - | - | 2 | - | - | - |
Antonio Cioffi | - | - | 2 | - | - | - |
Giuseppe D'Agostino | - | - | 2 | - | - | - | 106 | 77 | 71 | 29 | 29 | 7 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .