| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Jan Oblak | 38 | 38 | - | - | - | - |
Antoine Griezmann | 38 | 36 | 2 | 2 | 16 | 22 |
Jorge Koke | 35 | 34 | 1 | 1 | 6 | 5 |
Juanfran | 35 | 34 | 2 | 1 | 1 | 1 |
Fernandez Gabi | 35 | 34 | 1 | 1 | 6 | 1 |
Filipe Luis | 32 | 32 | 2 | - | - | 1 |
Diego Godin | 31 | 31 | 1 | - | 2 | 1 |
Saul Niguez | 30 | 26 | 12 | 4 | 4 | 4 |
Fernando Torres | 30 | 17 | 17 | 13 | 10 | 11 |
Yannick Carrasco | 29 | 16 | 14 | 13 | 15 | 4 |
Jose Maria Gimenez | 27 | 27 | 5 | - | - | 1 |
Angel Correa | 26 | 8 | 28 | 18 | 7 | 5 |
Oliver Torres | 21 | 9 | 18 | 12 | 9 | - |
Luciano Vietto | 19 | 12 | 21 | 7 | 11 | 1 |
Jackson Martinez | 15 | 8 | 9 | 7 | 6 | 2 |
Tiago | 14 | 12 | 2 | 2 | 2 | 1 |
Augusto Fernandez | 13 | 11 | 3 | 2 | 8 | - |
Thomas Partey | 13 | 3 | 18 | 10 | 2 | 2 |
Stefan Savic | 12 | 10 | 19 | 2 | - | - |
Lucas Hernandez | 10 | 8 | 8 | 2 | - | - |
Jesus Gamez | 10 | 7 | 24 | 3 | - | - |
Matias Kranevitter | 8 | 3 | 10 | 5 | 1 | - |
Guilherme Siqueira | 1 | 1 | 4 | - | - | - |
Nacho Monsalve | 1 | 1 | 2 | - | - | - |
Raul Garcia | 1 | - | 1 | 1 | - | - |
Theo Hernandez | - | - | 1 | - | - | - |
Amath Ndiaye Diedhiou | - | - | 1 | - | - | - |
Miguel Angel Moya | - | - | 38 | - | - | - |
Samu Villa | - | - | 2 | - | - | - | 524 | 418 | 266 | 106 | 106 | 62 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .