| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Samir Handanovic | 36 | 36 | - | - | - | - |
Jeison Murillo | 34 | 32 | 2 | 2 | 2 | 2 |
Ivan Perisic | 34 | 26 | 9 | 8 | 8 | 7 |
Mauro Icardi | 33 | 32 | 3 | 1 | 14 | 16 |
Joao Miranda | 32 | 31 | 1 | 1 | - | 1 |
Gary Medel | 31 | 29 | 5 | 2 | 6 | 1 |
Marcelo Brozovic | 31 | 24 | 13 | 7 | 4 | 4 |
Stevan Jovetic | 27 | 19 | 14 | 8 | 15 | 6 |
Geoffrey Kondogbia | 26 | 23 | 10 | 3 | 9 | 1 |
Felipo Melo | 26 | 21 | 10 | 5 | 4 | 1 |
Rodrigo Palacio | 26 | 14 | 22 | 12 | 9 | 2 |
Adem Ljajic | 24 | 15 | 18 | 9 | 8 | 3 |
Yuto Nagatomo | 23 | 20 | 16 | 3 | 2 | - |
Alex Telles | 21 | 18 | 17 | 3 | 8 | - |
Jonathan Biabiany | 21 | 8 | 26 | 13 | 5 | 1 |
Danilo D'Ambrosio | 20 | 18 | 17 | 2 | 1 | 2 |
Juan | 18 | 16 | 20 | 2 | 2 | - |
Fredy Guarin | 17 | 12 | 6 | 5 | 3 | 1 |
Eder | 14 | 8 | 9 | 6 | 5 | 1 |
Davide Santon | 11 | 10 | 23 | 1 | 3 | - |
Andrea Ranocchia | 9 | - | 19 | 9 | - | - |
Rey Manaj | 4 | - | 35 | 4 | - | - |
Martin Montoya | 3 | 3 | 18 | - | 1 | - |
Juan Carrizo | 2 | 2 | 36 | - | 1 | - |
Assane Demoya Gnoukouri | 2 | 1 | 35 | 1 | 1 | - |
Hernanes | 2 | - | 2 | 2 | - | - |
Ionut Radu | 1 | - | 4 | 1 | - | - |
Fabio Della Giovanna | 1 | - | 1 | 1 | - | - |
Ezequiel Schelotto | - | - | 1 | - | - | - |
Federico Dimarco | - | - | 3 | - | - | - |
Andrea Palazzi | - | - | 1 | - | - | - |
Razvan Popa | - | - | 2 | - | - | - |
Saphir Taider | - | - | 1 | - | - | - |
Senna Miangue | - | - | 2 | - | - | - |
Ze Turbo | - | - | 3 | - | - | - |
Marco Andreolli | - | - | 1 | - | - | - |
Loris Zonta | - | - | 2 | - | - | - |
Tommaso Berni | - | - | 21 | - | - | - |
Bright Gyamfi | - | - | 2 | - | - | - |
Dodo | - | - | 3 | - | - | - |
Enrico Baldini | - | - | 1 | - | - | - | 529 | 418 | 434 | 111 | 111 | 49 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .