| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Felipe Anderson | 35 | 21 | 17 | 14 | 9 | 7 |
Marco Parolo | 31 | 30 | 1 | 1 | 5 | 3 |
Keita Balde | 31 | 15 | 18 | 16 | 4 | 4 |
Antonio Candreva | 30 | 28 | 5 | 2 | 17 | 10 |
Senad Lulic | 30 | 28 | 3 | 2 | 6 | 3 |
Federico Marchetti | 29 | 29 | 1 | - | 2 | - |
Lucas Biglia | 27 | 26 | 1 | 1 | 3 | 4 |
Filip Dordevic | 27 | 16 | 15 | 11 | 10 | 3 |
Wesley Hoedt | 25 | 24 | 10 | 1 | 3 | - |
Sergej Milinkovic-Savic | 25 | 17 | 16 | 8 | 5 | 1 |
Mauricio | 24 | 19 | 15 | 5 | - | - |
Miroslav Klose | 24 | 14 | 14 | 10 | 9 | 7 |
Dusan Basta | 23 | 21 | 4 | 2 | 3 | - |
Danilo Cataldi | 20 | 16 | 20 | 4 | 7 | 1 |
Santiago Gentiletti | 19 | 19 | 8 | - | - | - |
Alessandro Matri | 19 | 7 | 19 | 12 | 7 | 4 |
Abdoulay Konko | 17 | 17 | 14 | - | 2 | - |
Ogenyi Onazi | 15 | 14 | 19 | 1 | 6 | 1 |
Stefan Radu | 13 | 13 | 7 | - | 3 | - |
Stefano Mauri | 12 | 6 | 24 | 6 | 5 | 1 |
Milan Bisevac | 11 | 11 | 2 | - | 1 | 1 |
Etrit Berisha | 11 | 9 | 25 | 2 | - | - |
Ricardo Kishna | 11 | 7 | 13 | 4 | 4 | 2 |
Patric | 9 | 6 | 24 | 3 | 1 | - |
Edson Braafheid | 6 | 3 | 29 | 3 | - | - |
Ravel Morrison | 4 | - | 23 | 4 | - | - |
Stefan de Vrij | 2 | 2 | - | - | - | - |
Franjo Prce | - | - | 5 | - | - | - |
Kristjan Matosevic | - | - | 8 | - | - | - |
Luca Germoni | - | - | 2 | - | - | - |
Antonio Rozzi | - | - | 2 | - | - | - |
Alessandro Murgia | - | - | 2 | - | - | - |
Guido Guerrieri | - | - | 33 | - | - | - |
Christopher Ikonomidis | - | - | 8 | - | - | - |
Simone Mattia | - | - | 3 | - | - | - |
Simone Palombi | - | - | 1 | - | - | - | 530 | 418 | 411 | 112 | 112 | 52 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .