| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Antonio Candreva | 37 | 35 | 2 | 2 | 11 | 12 |
Senad Lulic | 30 | 28 | 3 | 2 | 4 | 7 |
Ogenyi Onazi | 29 | 19 | 17 | 10 | 5 | 1 |
Cristian Ledesma | 27 | 25 | 9 | 2 | 4 | - |
Lorik Cana | 26 | 24 | 9 | 2 | 5 | 2 |
Lucas Biglia | 26 | 23 | 6 | 3 | 7 | 2 |
Stefan Radu | 25 | 25 | - | - | - | 2 |
Miroslav Klose | 25 | 22 | 3 | 3 | 7 | 7 |
Alvaro Gonzalez | 25 | 16 | 12 | 9 | 11 | 1 |
Keita Balde | 25 | 14 | 20 | 11 | 7 | 5 |
Abdoulay Konko | 21 | 21 | 1 | - | 2 | - |
Federico Marchetti | 21 | 21 | 5 | - | - | - |
Giuseppe Biava | 20 | 19 | 7 | 1 | 2 | 1 |
Brayan Perea | 19 | 8 | 24 | 11 | 3 | 1 |
Luis Pedro Cavanda | 18 | 15 | 21 | 3 | 6 | 1 |
Michael Ciani | 18 | 13 | 20 | 5 | 2 | 1 |
Etrit Berisha | 17 | 17 | 16 | - | - | - |
Hernanes | 17 | 14 | 4 | 3 | 6 | 3 |
Andre Dias | 16 | 14 | 9 | 2 | 2 | 1 |
Honorato Ederson | 15 | 6 | 13 | 9 | 7 | 1 |
Sergio Floccari | 14 | 5 | 16 | 9 | 3 | - |
Felipe Anderson | 13 | 7 | 28 | 6 | 7 | - |
Diego Novaretti | 12 | 9 | 18 | 3 | 2 | - |
Stefano Mauri | 12 | 8 | 7 | 4 | 6 | 4 |
Bruno Pereirinha | 11 | 9 | 19 | 2 | 2 | - |
Helder Postiga | 5 | 1 | 5 | 4 | 1 | - |
Joseph Marie Minala | 3 | - | 6 | 3 | - | - |
Mamadou Tounkara | 1 | - | 1 | 1 | - | - |
Luca Crecco | 1 | - | 10 | 1 | - | - |
Gael Kakuta | 1 | - | 15 | 1 | - | - |
Antonio Rozzi | - | - | 2 | - | - | - |
Guido Guerrieri | - | - | 15 | - | - | - |
Thomas Strakosha | - | - | 36 | - | - | - |
Josip Elez | - | - | 9 | - | - | - |
Vinicius Freitas | - | - | 14 | - | - | - |
Libor Kozak | - | - | 1 | - | - | - |
Riccardo Serpieri | - | - | 1 | - | - | - |
Albano Bizzarri | - | - | 2 | - | - | - | 530 | 418 | 406 | 112 | 112 | 52 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .