| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Pedro Obiang | 34 | 32 | 2 | 2 | 2 | 1 |
Marcelo Estigarribia | 34 | 29 | 9 | 5 | 15 | 2 |
Daniele Gastaldello | 33 | 33 | - | - | 2 | 1 |
Sergio Romero | 32 | 32 | 3 | - | - | - |
Andrea Poli | 31 | 31 | - | - | 14 | 3 |
Mauro Icardi | 31 | 24 | 11 | 7 | 8 | 10 |
Eder | 30 | 24 | 7 | 6 | 14 | 7 |
Andrea Costa | 27 | 27 | - | - | 1 | 1 |
Gianni Munari | 27 | 14 | 20 | 13 | 4 | 3 |
Jonathan Rossini | 25 | 24 | 13 | 1 | 1 | - |
Nenad Krsticic | 25 | 22 | 3 | 3 | 8 | 1 |
Lorenzo De Silvestri | 24 | 19 | 15 | 5 | 4 | 2 |
Roberto Soriano | 24 | 8 | 28 | 16 | 4 | - |
Gaetano Berardi | 21 | 18 | 13 | 3 | 7 | - |
Shkodran Mustafi | 17 | 12 | 22 | 5 | 2 | - |
Maxi Lopez | 17 | 9 | 17 | 8 | 3 | 4 |
Enzo Maresca | 16 | 15 | 13 | 1 | 6 | 3 |
Angelo Palombo | 15 | 15 | 2 | - | 1 | - |
Gianluca Sansone | 14 | 6 | 9 | 8 | 4 | 2 |
Fernando Tissone | 12 | 6 | 13 | 6 | 1 | - |
Paolo Castellini | 7 | 4 | 33 | 3 | - | - |
Simon Poulsen | 7 | 3 | 28 | 4 | 3 | - |
Nicola Pozzi | 6 | 1 | 6 | 5 | 1 | 1 |
Renan | 5 | 3 | 32 | 2 | 2 | - |
Angelo da Costa | 4 | 4 | 20 | - | - | - |
Tommaso Berni | 3 | 2 | 31 | 1 | - | - |
Juan Antonio | 2 | - | 5 | 2 | - | - |
Matias Rodriguez | 1 | 1 | 9 | - | - | - |
Andelko Savic | 1 | - | 11 | 1 | - | - |
Daniele Padelli | - | - | 1 | - | - | - |
Wladimiro Falcone | - | - | 9 | - | - | - | 525 | 418 | 385 | 107 | 107 | 41 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .