| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Fernando Muslera | 16 | 16 | - | - | - | - |
Edinson Cavani | 16 | 14 | 2 | 2 | 1 | 5 |
Egidio Arevalo | 15 | 14 | 1 | 1 | 2 | - |
Cristian Rodriguez | 15 | 8 | 8 | 7 | 4 | 2 |
Diego Godin | 14 | 14 | - | - | - | - |
Luis Suarez | 14 | 14 | - | - | 2 | 11 |
Maxi Pereira | 14 | 14 | - | - | 4 | 1 |
Diego Lugano | 13 | 13 | - | - | 2 | 2 |
Diego Forlan | 13 | 11 | 3 | 2 | 5 | 2 |
Alvaro Gonzalez | 12 | 6 | 9 | 6 | 3 | - |
Alvaro Pereira | 11 | 10 | 5 | 1 | 4 | - |
Diego Perez | 10 | 10 | 3 | - | 6 | - |
Gaston Ramirez | 10 | 4 | 8 | 6 | 3 | - |
Martin Caceres | 8 | 8 | - | - | 1 | - |
Walter Gargano | 8 | 5 | 8 | 3 | 3 | - |
Jorge Fucile | 5 | 3 | 2 | 2 | - | - |
Nicolas Lodeiro | 4 | 3 | 9 | 1 | 2 | - |
Sebastian Eguren | 4 | - | 12 | 4 | - | 1 |
Jose Maria Gimenez | 3 | 2 | 1 | 1 | - | - |
Andres Scotti | 3 | 2 | 11 | 1 | - | - |
Cristhian Stuani | 3 | 1 | 5 | 2 | 1 | 1 |
Mauricio Victorino | 2 | 2 | 3 | - | 1 | - |
Sebastian Coates | 2 | 1 | 8 | 1 | - | - |
Sebastian Abreu | 2 | - | 7 | 2 | - | - |
Alejandro Silva | 2 | - | 3 | 2 | - | - |
Matias Aguirregaray | 1 | 1 | 6 | - | 1 | - |
Alvaro Fernandez | 1 | - | 5 | 1 | - | - |
Martin Silva | - | - | 10 | - | - | - |
Rodrigo Munoz | - | - | 3 | - | - | - |
Sebastian Fernandez | - | - | 5 | - | - | - |
Chori Castro | - | - | 1 | - | - | - |
Abel Hernandez | - | - | 6 | - | - | - |
Juan Castillo | - | - | 8 | - | - | - | 221 | 176 | 152 | 45 | 45 | 25 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .