| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Kwadwo Asamoah | 38 | 37 | 1 | 1 | 3 | 2 |
Antonio Di Natale | 36 | 35 | 1 | 1 | 20 | 28 |
Cristian Zapata | 35 | 35 | - | - | 1 | 2 |
Gokhan Inler | 35 | 35 | - | - | 6 | 3 |
Giampiero Pinzi | 35 | 31 | 4 | 4 | 4 | 1 |
Samir Handanovic | 34 | 34 | - | - | - | - |
Mehdi Benatia | 34 | 34 | 3 | - | 2 | 3 |
Mauricio Isla | 34 | 34 | 1 | - | 7 | 2 |
Alexis Sanchez | 31 | 27 | 6 | 4 | 9 | 12 |
Pablo Armero | 30 | 28 | 5 | 2 | 11 | 2 |
Muarizio Domizzi | 30 | 28 | 2 | 2 | 5 | 2 |
German Denis | 26 | 8 | 24 | 18 | 6 | 4 |
Andrea Coda | 22 | 16 | 17 | 6 | 4 | - |
Almen Abdi | 19 | 6 | 21 | 13 | 5 | - |
Giovanni Pasquale | 17 | 10 | 26 | 7 | 5 | - |
Bernardo Corradi | 17 | - | 38 | 17 | 1 | 1 |
Antonio Floro Flores | 12 | 10 | 7 | 2 | 7 | 3 |
Juan Cuadrado | 9 | 3 | 19 | 6 | 3 | - |
Emmanuel Agyemang-Badu | 8 | 2 | 26 | 6 | 1 | - |
Gabriele Angella | 8 | 1 | 16 | 7 | - | - |
Emanuele Belardi | 3 | 3 | 34 | - | - | - |
Matej Vydra | 2 | - | 4 | 2 | - | - |
Rafael Romo | 1 | 1 | - | - | - | - |
Joel Ekstrand | 1 | - | 3 | 1 | - | - |
Cristian Battocchio | 1 | - | 2 | 1 | - | - |
Jan Koprivec | - | - | 4 | - | - | - |
Steve Leo Beleck | - | - | 1 | - | - | - | 518 | 418 | 265 | 100 | 100 | 65 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .