| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Simao Sabrosa | 6 | 6 | - | - | 2 | 1 |
Diego Forlan | 6 | 5 | 1 | 1 | 3 | 1 |
Tiago | 6 | 4 | 2 | 2 | 2 | 1 |
Raul Garcia | 6 | 4 | 2 | 2 | 2 | - |
Diego Costa | 6 | 3 | 3 | 3 | 1 | 1 |
Alvaro Dominguez | 5 | 5 | - | - | - | - |
David de Gea | 5 | 5 | 1 | - | - | - |
Tomas Ujfalusi | 4 | 4 | - | - | - | - |
Paulo Assuncao | 4 | 4 | 2 | - | 1 | - |
Jose Antonio Reyes | 4 | 3 | 2 | 1 | - | - |
Luis Perea | 4 | 3 | 3 | 1 | - | - |
Sergio Aguero | 4 | 3 | 1 | 1 | 1 | 3 |
Mario Suarez | 4 | 2 | 4 | 2 | 1 | - |
Fran Merida | 4 | 1 | 5 | 3 | 1 | 1 |
Antonio Lopez | 3 | 3 | 3 | - | 1 | - |
Filipe Luis | 3 | 3 | 2 | - | - | - |
Diego Godin | 3 | 3 | 1 | - | - | 1 |
Juan Valera | 3 | 3 | 3 | - | 1 | - |
Ignacio Camacho | 2 | 1 | 2 | 1 | 1 | - |
Joel Robles | 1 | 1 | 5 | - | - | - | 83 | 66 | 42 | 17 | 17 | 9 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .