| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Heiko Westermann | 34 | 34 | - | - | - | 2 |
Ze Roberto | 31 | 31 | - | - | 2 | 1 |
Frank Rost | 30 | 30 | - | - | 1 | - |
Jonathan Pitroipa | 26 | 20 | 10 | 6 | 11 | 2 |
Ruud van Nistelrooy | 25 | 19 | 7 | 6 | 6 | 7 |
Paulo Guerrero | 25 | 18 | 10 | 7 | 8 | 4 |
David Jarolim | 24 | 23 | 7 | 1 | 8 | - |
Eljero Elia | 24 | 18 | 7 | 6 | 10 | 2 |
Gojko Kacar | 23 | 18 | 9 | 5 | 3 | 2 |
Mladen Petric | 22 | 18 | 6 | 4 | 3 | 11 |
Guy Demel | 21 | 19 | 6 | 2 | 4 | - |
Piotr Trochowski | 21 | 13 | 19 | 8 | 2 | 2 |
Dennis Aogo | 20 | 20 | - | - | 1 | - |
Joris Mathijsen | 19 | 19 | - | - | 2 | 2 |
Tomas Rincon | 19 | 12 | 13 | 7 | 2 | - |
Anis Ben Hatira | 18 | 12 | 11 | 6 | 6 | 3 |
Marcell Jansen | 16 | 12 | 8 | 4 | 5 | 2 |
Heung Min Son | 13 | 8 | 12 | 5 | 4 | 3 |
Robert Tesche | 11 | 5 | 26 | 6 | - | - |
Maxim Choupo-Moting | 10 | 4 | 15 | 6 | 2 | 2 |
Dennis Diekmeier | 8 | 8 | 1 | - | 3 | - |
Collin Benjamin | 8 | 3 | 14 | 5 | - | - |
Jaroslav Drobny | 5 | 4 | 24 | 1 | - | - |
Tunay Torun | 5 | 4 | 8 | 1 | 4 | - |
Muhamed Besic | 3 | 2 | 10 | 1 | - | - |
Gerrit Pressel | - | - | 1 | - | - | - |
Lennard Sowah | - | - | 1 | - | - | - |
Tom Mickel | - | - | 10 | - | - | - |
Romeo Castelen | - | - | 1 | - | - | - | 461 | 374 | 236 | 87 | 87 | 45 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .