| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Daniele De Rossi | 8 | 8 | - | - | - | 1 |
John Arne Riise | 8 | 8 | - | - | 1 | 2 |
David Pizarro | 7 | 6 | 1 | 1 | 1 | 1 |
Jeremy Menez | 7 | 3 | 4 | 4 | 2 | - |
Nicolas Burdisso | 6 | 6 | 1 | - | - | - |
Julio Baptista | 6 | 4 | 3 | 2 | 1 | - |
Mirko Vucinic | 6 | 4 | 2 | 2 | 3 | 2 |
Rodrigo Taddei | 6 | 4 | 2 | 2 | 2 | - |
Philippe Mexes | 5 | 5 | 1 | - | - | - |
Simone Perrotta | 5 | 4 | 2 | 1 | - | 1 |
Julio Sergio | 5 | 4 | 1 | 1 | 1 | - |
Stefano Okaka | 4 | 4 | 2 | - | 2 | 2 |
Marco Motta | 4 | 4 | 2 | - | - | - |
Juan | 4 | 3 | 3 | 1 | 1 | - |
Alessio Cerci | 4 | 3 | 2 | 1 | 3 | 2 |
Matteo Brighi | 4 | 3 | 3 | 1 | 2 | - |
Marco Andreolli | 4 | 3 | 2 | 1 | - | 1 |
Doni | 4 | 3 | 2 | 1 | 1 | - |
Stefano Guberti | 3 | 2 | 3 | 1 | 1 | - |
Cicinho | 2 | 2 | - | - | 2 | - |
Marco Cassetti | 2 | 2 | 4 | - | - | - |
Francesco Totti | 2 | 2 | 1 | - | - | 1 |
Max Tonetto | 2 | - | 3 | 2 | - | - |
Bogdan Lobont | 1 | 1 | 3 | - | - | - |
Stefano Pettinari | 1 | - | 1 | 1 | - | - |
Filippo Scardina | 1 | - | 1 | 1 | - | 1 |
Artur Moraes | - | - | 2 | - | - | - |
Leandro Greco | - | - | 3 | - | - | - |
Ricardo Faty | - | - | 2 | - | - | - | 111 | 88 | 56 | 23 | 23 | 14 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .