| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Joan Capdevila | 8 | 7 | 1 | 1 | - | 1 |
Diego Lopez | 8 | 7 | 1 | 1 | 1 | - |
Nilmar | 8 | 6 | 2 | 2 | 1 | 1 |
Angel Lopez | 7 | 7 | - | - | - | - |
Ivan Marcano | 7 | 6 | 1 | 1 | - | - |
Cani | 7 | 5 | 2 | 2 | 3 | 1 |
Gonzalo Rodriguez | 6 | 6 | - | - | 2 | - |
Robert Pires | 6 | 6 | 2 | - | 5 | 2 |
Sebastian Eguren | 6 | 6 | - | - | - | 1 |
Bruno Soriano | 6 | 6 | 2 | - | 2 | - |
Giuseppe Rossi | 6 | 3 | 3 | 3 | 2 | 2 |
Joseba Llorente | 5 | 4 | 3 | 1 | 2 | - |
Marcos Senna | 5 | 3 | 2 | 2 | - | 2 |
Diego Godin | 4 | 4 | 2 | - | 1 | - |
Damian Escudero | 4 | 2 | 4 | 2 | - | - |
Ariel Ibagaza | 3 | 2 | 2 | 1 | 1 | - |
Jonathan Pereira | 3 | 2 | 3 | 1 | 2 | - |
David Fuster | 2 | 2 | 4 | - | 1 | - |
Xavi Oliva | 2 | 1 | 7 | 1 | - | - |
Santi Cazorla | 2 | 1 | 1 | 1 | - | - |
Javier Magro Matilla | 2 | - | 2 | 2 | - | - |
Kiko Olivas | 1 | 1 | - | - | 1 | - |
Javi Venta | 1 | 1 | 5 | - | - | - |
Jefferson Montero | 1 | - | 1 | 1 | - | - |
Marco Ruben | 1 | - | 2 | 1 | - | 1 |
Mateo Musacchio | 1 | - | 2 | 1 | - | - |
Fabricio Fuentas | - | - | 2 | - | - | - | 112 | 88 | 56 | 24 | 24 | 11 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .