| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Diego | 33 | 31 | 2 | 2 | 18 | 5 |
Giorgio Chiellini | 32 | 32 | 1 | - | - | 3 |
Amauri | 30 | 24 | 8 | 6 | 7 | 5 |
Felipo Melo | 29 | 28 | 2 | 1 | 5 | 4 |
Claudio Marchisio | 28 | 27 | 1 | 1 | 10 | 3 |
Gianluigi Buffon | 27 | 27 | - | - | 1 | - |
Fabio Cannavaro | 27 | 27 | 6 | - | 1 | - |
Fabio Grosso | 26 | 22 | 11 | 4 | 4 | 2 |
Christian Poulsen | 25 | 19 | 10 | 6 | 4 | - |
Mauro Camoranesi | 24 | 14 | 13 | 10 | 8 | 2 |
Paolo De Ceglie | 24 | 14 | 16 | 10 | 5 | - |
Alessandro Del Piero | 23 | 18 | 10 | 5 | 11 | 9 |
Nicola Legrottaglie | 19 | 18 | 19 | 1 | 1 | 1 |
Zdenek Grygera | 19 | 15 | 12 | 4 | 3 | - |
David Trezeguet | 19 | 13 | 14 | 6 | 4 | 7 |
Mohamed Sissoko | 17 | 14 | 3 | 3 | 4 | - |
Jonathan Zebina | 16 | 13 | 9 | 3 | 4 | - |
Antonio Candreva | 16 | 8 | 8 | 8 | 2 | 2 |
Vincenzo Iaquinta | 15 | 12 | 6 | 3 | 4 | 6 |
Martin Caceres | 15 | 11 | 5 | 4 | - | 1 |
Hasan Salihamidzic | 15 | 6 | 12 | 9 | 3 | 2 |
Sebastian Giovinco | 14 | 5 | 18 | 9 | 4 | 1 |
Alex Manninger | 11 | 9 | 26 | 2 | - | - |
Tiago | 7 | 4 | 6 | 3 | 3 | - |
Cristian Molinaro | 5 | 4 | 8 | 1 | 3 | - |
Michele Paolucci | 4 | 1 | 7 | 3 | - | - |
Antonio Chimenti | 2 | 2 | 5 | - | - | - |
Luca Marrone | 2 | - | 9 | 2 | - | - |
Ciro Immobile | 2 | - | 7 | 2 | - | - |
Manuel Giandonato | 1 | - | 1 | 1 | - | - |
Iago Falque | - | - | 1 | - | - | - |
Fausto Rossi | - | - | 1 | - | - | - |
Andre Cuneaz | - | - | 1 | - | - | 1 |
Lorenzo Ariaudo | - | - | 1 | - | - | - |
Carlo Pinsoglio | - | - | 7 | - | - | - | 527 | 418 | 266 | 109 | 109 | 54 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .