| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Roel Brouwers | 34 | 34 | - | - | - | 8 |
Juan Arango | 34 | 33 | 1 | 1 | 11 | 2 |
Marco Reus | 33 | 27 | 7 | 6 | 8 | 8 |
Tobias Levels | 32 | 32 | - | - | 1 | - |
Dante | 32 | 32 | - | - | - | 3 |
Raul Bobadilla | 30 | 25 | 5 | 5 | 16 | 4 |
Logan Bailly | 29 | 29 | - | - | - | - |
Michael Bradley | 29 | 28 | 3 | 1 | 5 | 2 |
Torben Marx | 28 | 28 | - | - | 7 | - |
Karim Matmour | 25 | 18 | 7 | 7 | 12 | 1 |
Rob Friend | 25 | 11 | 16 | 14 | 5 | 3 |
Roberto Colautti | 23 | 15 | 17 | 8 | 13 | 5 |
Filip Daems | 18 | 18 | - | - | 3 | 1 |
Marcel Meeuwis | 18 | 14 | 19 | 4 | 3 | - |
Jean-Sebastian Jaures | 16 | 14 | 17 | 2 | 1 | - |
Thomas Kleine | 14 | 2 | 31 | 12 | - | - |
Patrick Herrmann | 13 | 3 | 14 | 10 | 3 | 1 |
Oliver Neuville | 11 | 1 | 15 | 10 | 1 | - |
Tony Jantschke | 6 | 2 | 21 | 4 | - | - |
Christofer Heimeroth | 5 | 5 | 29 | - | - | - |
Paul Stalteri | 3 | 2 | 6 | 1 | 1 | - |
Moses Lamidi | 3 | 1 | 10 | 2 | 1 | - |
Fabian Backer | 2 | - | 7 | 2 | - | 1 |
Roman Neustadter | 2 | - | 8 | 2 | - | - |
Frederic Lohe | - | - | 4 | - | - | - |
Marc-Andre ter Stegen | - | - | 1 | - | - | - | 465 | 374 | 238 | 91 | 91 | 39 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .