| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Mark Schwarzer | 37 | 37 | - | - | - | - |
Aaron Hughes | 34 | 34 | 1 | - | - | - |
Brede Hangeland | 32 | 32 | - | - | 2 | 1 |
Damien Duff | 32 | 30 | 2 | 2 | 10 | 6 |
Chris Baird | 32 | 29 | 9 | 3 | 1 | - |
Clint Dempsey | 29 | 27 | 2 | 2 | 6 | 7 |
Paul Konchesky | 27 | 27 | - | - | 2 | 1 |
Bobby Zamora | 27 | 27 | - | - | 11 | 8 |
Zoltan Gera | 27 | 19 | 14 | 8 | 6 | 2 |
Danny Murphy | 25 | 25 | 3 | - | 7 | 5 |
Jonathan Greening | 23 | 15 | 20 | 8 | 5 | 1 |
Erik Nevland | 23 | 12 | 20 | 11 | 7 | 3 |
John Pantsil | 22 | 22 | 2 | - | 4 | - |
Dickson Etuhu | 20 | 14 | 10 | 6 | 2 | - |
Simon Davies | 17 | 12 | 6 | 5 | 5 | - |
Chris Smalling | 12 | 9 | 24 | 3 | - | - |
Kagisho Dikgacoi | 12 | 7 | 14 | 5 | 2 | - |
Bjorn Helge Riise | 12 | 5 | 26 | 7 | 3 | - |
Stefano Okaka | 11 | 3 | 12 | 8 | 3 | 2 |
David Elm | 10 | 3 | 9 | 7 | 2 | 1 |
Nicky Shorey | 9 | 9 | 4 | - | - | - |
Diomansy Kamara | 9 | 5 | 6 | 4 | 4 | 1 |
Andrew Johnson | 8 | 7 | 2 | 1 | 3 | - |
Stephen Kelly | 8 | 7 | 16 | 1 | 3 | - |
Eddie Johnson | 2 | - | 5 | 2 | - | - |
Ki-Hyeon Seol | 2 | - | 6 | 2 | - | - |
Fredrik Stoor | 2 | - | 7 | 2 | - | - |
David Stockdale | 1 | 1 | 3 | - | - | - |
Toni Kallio | 1 | - | 5 | 1 | - | - |
Pascal Zuberbuhler | - | - | 35 | - | - | - |
Matthew Briggs | - | - | 1 | - | - | - |
Andranik Teymourian | - | - | 1 | - | - | - | 506 | 418 | 265 | 88 | 88 | 38 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .