| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Andrea Barzagli | 34 | 34 | - | - | - | - |
Marcel Schafer | 34 | 34 | - | - | 1 | - |
Christian Gentner | 34 | 32 | 2 | 2 | 18 | 4 |
Josue | 32 | 32 | 1 | - | 2 | - |
Edin Dzeko | 32 | 29 | 4 | 3 | 3 | 26 |
Zvjezdan Misimovic | 31 | 31 | - | - | 12 | 6 |
Diego Benaglio | 31 | 31 | - | - | 2 | - |
Sascha Riether | 28 | 26 | 2 | 2 | 8 | 2 |
Ashkan Dejagah | 27 | 13 | 16 | 14 | 10 | 3 |
Grafite | 25 | 25 | - | - | 10 | 28 |
Makoto Hasebe | 25 | 16 | 13 | 9 | 10 | - |
Alexander Madlung | 24 | 13 | 19 | 11 | 2 | 3 |
Jan Simunek | 17 | 14 | 10 | 3 | - | - |
Peter Pekarik | 16 | 13 | 4 | 3 | 5 | - |
Cristian Zaccardo | 14 | 8 | 20 | 6 | 5 | 1 |
Ricardo Costa | 11 | 10 | 17 | 1 | 1 | 3 |
Yoshito Okubo | 9 | 1 | 14 | 8 | 1 | - |
Caiuby | 8 | - | 14 | 8 | 1 | 1 |
Mahir Saglik | 8 | - | 13 | 8 | 1 | 1 |
Jonathan Santana | 6 | 3 | 3 | 3 | 2 | - |
Sebastian Schindzielorz | 6 | 3 | 9 | 3 | 1 | - |
Jacek Krzynowek | 6 | 2 | 7 | 4 | - | - |
Andre Lenz | 5 | 3 | 28 | 2 | - | - |
Alexander Esswein | 3 | - | 7 | 3 | - | - |
Rodrigo Alvim | 2 | - | 16 | 2 | - | - |
Sergej Karimov | 1 | 1 | - | - | 1 | - |
Daniel Reiche | 1 | - | 1 | 1 | - | - |
Vlad Munteanu | - | - | 1 | - | - | - |
Dorinel Munteanu | - | - | 1 | - | - | - |
Patrick Platins | - | - | 1 | - | - | - |
Marwin Hitz | - | - | 2 | - | - | - | 470 | 374 | 225 | 96 | 96 | 78 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .