| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Patrick Helmes | 34 | 34 | - | - | 18 | 21 |
Stefan Kiessling | 34 | 34 | - | - | 5 | 12 |
Simon Rolfes | 33 | 33 | - | - | - | 3 |
Renato Augusto | 33 | 31 | 2 | 2 | 10 | 2 |
Rene Adler | 31 | 31 | - | - | - | - |
Tranquillo Barnetta | 31 | 27 | 4 | 4 | 13 | 4 |
Manuel Friedrich | 30 | 30 | - | - | 1 | 3 |
Michal Kadlec | 30 | 29 | 2 | 1 | - | 3 |
Arturo Vidal | 29 | 27 | 2 | 2 | 14 | 3 |
Henrique | 27 | 26 | 2 | 1 | 2 | - |
Gonzalo Castro | 27 | 25 | 2 | 2 | 4 | 2 |
Sascha Dum | 20 | 2 | 23 | 18 | 2 | - |
Theofanis Gekas | 15 | - | 16 | 15 | - | 2 |
Pirmin Schwegler | 14 | 6 | 19 | 8 | 4 | - |
Lukas Sinkiewicz | 13 | 11 | 5 | 2 | 2 | - |
Angelos Charisteas | 13 | - | 16 | 13 | - | 1 |
Karim Haggui | 11 | 8 | 16 | 3 | - | 1 |
Toni Kroos | 10 | 6 | 6 | 4 | 4 | 1 |
Constant Djakpa | 8 | 5 | 19 | 3 | 3 | - |
Tomasz Zdebel | 4 | 4 | 5 | - | 2 | - |
Benedikt Fernandez | 3 | 3 | 5 | - | - | - |
Hans Sarpei | 3 | 2 | 10 | 1 | 2 | - |
Richard Sukuta-Pasu | 3 | - | 11 | 3 | - | - |
Jens Hegeler | 2 | - | 11 | 2 | - | - |
Dmitri Bulykin | 1 | - | 1 | 1 | - | - |
Bernd Schneider | 1 | - | 4 | 1 | - | - |
Eric Domaschke | - | - | 9 | - | - | - |
Marcel Risse | - | - | 3 | - | - | - |
Stefan Reinartz | - | - | 6 | - | - | - |
Gabor Kiraly | - | - | 15 | - | - | - |
Vratislav Gresko | - | - | 1 | - | - | - | 460 | 374 | 215 | 86 | 86 | 58 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .