| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Maynor Figueroa | 38 | 38 | - | - | 5 | 1 |
Titus Bramble | 35 | 35 | 2 | - | 2 | 1 |
Mario Melchiot | 34 | 33 | 1 | 1 | 4 | - |
Lee Cattermole | 33 | 33 | - | - | 8 | 1 |
Christopher Kirkland | 32 | 32 | - | - | 1 | - |
Luis Antonio Valencia | 31 | 31 | - | - | 3 | 3 |
Paul Scharner | 29 | 27 | 5 | 2 | 4 | - |
Amr Zaki | 29 | 22 | 7 | 7 | 11 | 10 |
Emmerson Boyce | 27 | 26 | 9 | 1 | 1 | 1 |
Michael Brown | 25 | 18 | 19 | 7 | 6 | - |
Wilson Palacios | 21 | 21 | - | - | 6 | - |
Emile Heskey | 20 | 20 | - | - | 5 | 3 |
Olivier Kapo | 19 | 10 | 16 | 9 | 6 | 1 |
Daniel de Ridder | 18 | 5 | 30 | 13 | 5 | - |
Henri Camara | 17 | 3 | 20 | 14 | 2 | 2 |
Jason Koumas | 16 | 5 | 25 | 11 | 2 | - |
Hugo Rodallega | 15 | 9 | 7 | 6 | - | 3 |
Charles N'Zogbia | 13 | 13 | - | - | 4 | 1 |
Ryan Taylor | 12 | 11 | 6 | 1 | 7 | 2 |
Hossam Mido | 12 | 10 | 2 | 2 | 6 | 2 |
Ben Watson | 10 | 6 | 9 | 4 | 2 | 2 |
Kevin Kilbane | 10 | 3 | 17 | 7 | 2 | - |
Richard Kingson | 4 | 3 | 14 | 1 | - | - |
Mike Pollitt | 3 | 3 | 28 | - | - | - |
Antoine Sibierski | 3 | - | 7 | 3 | - | - |
Erik Edman | 2 | - | 19 | 2 | - | - |
Won-hee Cho | 1 | 1 | 2 | - | 1 | - |
Jonathon Routledge | 1 | - | 5 | 1 | - | - |
Callum McManaman | 1 | - | 2 | 1 | - | - |
Carlo Nash | - | - | 1 | - | - | - |
Tomasz Cywka | - | - | 8 | - | - | - |
Joe Holt | - | - | 1 | - | - | - |
Tomasz Kupisz | - | - | 2 | - | - | - | 511 | 418 | 264 | 93 | 93 | 33 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .