| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Frank Lampard | 37 | 37 | - | - | 2 | 12 |
Nicolas Anelka | 37 | 33 | 4 | 4 | 12 | 19 |
Petr Cech | 35 | 35 | - | - | - | - |
John Terry | 35 | 35 | - | - | 1 | 1 |
Jose Bosingwa | 34 | 34 | - | - | 9 | 2 |
Mikel John Obi | 34 | 33 | 2 | 1 | 6 | - |
Ashley Cole | 34 | 33 | 2 | 1 | 2 | 1 |
Florent Malouda | 31 | 24 | 9 | 7 | 11 | 6 |
Michael Ballack | 29 | 22 | 8 | 7 | 6 | 1 |
Salomon Kalou | 27 | 17 | 19 | 10 | 11 | 6 |
Alex Costa | 24 | 22 | 10 | 2 | 2 | 2 |
Deco | 24 | 17 | 8 | 7 | 6 | 3 |
Didier Drogba | 24 | 15 | 10 | 9 | 6 | 5 |
Juliano Belletti | 20 | 5 | 26 | 15 | 3 | 3 |
Branislav Ivanovic | 16 | 11 | 23 | 5 | - | - |
Joe Cole | 14 | 14 | - | - | 13 | 2 |
Ricardo Carvalho | 12 | 11 | 2 | 1 | 1 | 1 |
Michael Essien | 11 | 10 | 1 | 1 | 5 | 1 |
Franco Di Santo | 8 | - | 19 | 8 | - | - |
Paulo Ferreira | 7 | 1 | 20 | 6 | - | - |
Wayne Bridge | 6 | 3 | 13 | 3 | 1 | - |
Michael Mancienne | 4 | 2 | 15 | 2 | 2 | - |
Ricardo Quaresma | 4 | 1 | 6 | 3 | 1 | - |
Miroslav Stoch | 4 | - | 11 | 4 | - | - |
Carlo Cudicini | 2 | 2 | 12 | - | - | - |
Scott Sinclair | 2 | - | 9 | 2 | - | - |
Hilario | 1 | 1 | 25 | - | - | - |
Mineiro | 1 | - | 7 | 1 | - | - |
Shaun Wright-Phillips | 1 | - | 1 | 1 | - | - |
Michael Woods | - | - | 1 | - | - | - |
Gael Kakuta | - | - | 1 | - | - | - |
Rhys Taylor | - | - | 1 | - | - | - | 518 | 418 | 265 | 100 | 100 | 65 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .