| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Aaron Hughes | 38 | 38 | - | - | 2 | - |
Mark Schwarzer | 38 | 38 | - | - | - | - |
Danny Murphy | 38 | 38 | - | - | 11 | 5 |
John Pantsil | 37 | 37 | - | - | 3 | - |
Brede Hangeland | 37 | 37 | - | - | - | 1 |
Paul Konchesky | 36 | 36 | - | - | 1 | 1 |
Bobby Zamora | 35 | 32 | 4 | 3 | 16 | 2 |
Clint Dempsey | 35 | 28 | 10 | 7 | 8 | 7 |
Simon Davies | 33 | 33 | - | - | 7 | 2 |
Zoltan Gera | 32 | 20 | 15 | 12 | 9 | 2 |
Andrew Johnson | 31 | 30 | 1 | 1 | 7 | 7 |
Dickson Etuhu | 21 | 19 | 5 | 2 | 5 | 1 |
Erik Nevland | 21 | 4 | 34 | 17 | 4 | 4 |
Jimmy Bullard | 18 | 18 | - | - | 6 | 2 |
Diomansy Kamara | 12 | 3 | 11 | 9 | - | 4 |
Chris Baird | 10 | 3 | 22 | 7 | 1 | - |
Olivier Dacourt | 9 | - | 16 | 9 | - | - |
Leon Andreasen | 6 | - | 16 | 6 | - | - |
Ki-Hyeon Seol | 4 | 2 | 5 | 2 | 2 | 1 |
Toni Kallio | 3 | 2 | 26 | 1 | 1 | - |
Fredrik Stoor | 2 | - | 29 | 2 | - | - |
Robert Milsom | 1 | - | 3 | 1 | - | - |
Julian Gray | 1 | - | 21 | 1 | - | - |
Andranik Teymourian | 1 | - | 4 | 1 | - | - |
Chris Smalling | 1 | - | 5 | 1 | - | - |
Wayne Brown | 1 | - | 1 | 1 | - | - |
Pascal Zuberbuhler | - | - | 37 | - | - | - |
David Stockdale | - | - | 1 | - | - | - | 501 | 418 | 266 | 83 | 83 | 39 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .