| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Victor Valdes | 35 | 35 | 2 | - | - | - |
Xavi | 35 | 33 | 3 | 2 | 5 | 7 |
Andres Iniesta | 31 | 28 | 4 | 3 | - | 3 |
Bojan Krkic | 31 | 14 | 19 | 17 | 8 | 9 |
Carles Puyol | 30 | 29 | 1 | 1 | 5 | - |
Eric Abidal | 30 | 28 | 3 | 2 | 1 | - |
Thierry Henry | 30 | 27 | 3 | 3 | 8 | 12 |
Gianluca Zambrotta | 29 | 25 | 5 | 4 | 8 | - |
Lionel Messi | 28 | 23 | 5 | 5 | 10 | 10 |
Giovani Dos Santos | 28 | 10 | 19 | 18 | 7 | 3 |
Gabriel Milito | 27 | 26 | 1 | 1 | 3 | 1 |
Yaya Toure | 26 | 25 | 1 | 1 | 10 | 1 |
Rafael Marquez (Mex) | 23 | 15 | 9 | 8 | 3 | 2 |
Eidur Gudjohnsen | 23 | 12 | 16 | 11 | 9 | 2 |
Samuel Eto'o | 18 | 18 | - | - | 4 | 16 |
Lillian Thuram | 18 | 17 | 8 | 1 | 4 | - |
Deco | 18 | 14 | 5 | 4 | 7 | 1 |
Ronaldinho Gaucho | 17 | 13 | 4 | 4 | 6 | 8 |
Silvinho | 14 | 10 | 12 | 4 | 2 | - |
Oleguer | 12 | 7 | 9 | 5 | 1 | - |
Edmilson | 11 | 5 | 6 | 6 | 4 | - |
Jose Manuel Pinto | 3 | 3 | 2 | - | - | - |
Santiago Ezquerro | 3 | 1 | 7 | 2 | 1 | - |
Pedro Rodriguez | 1 | - | 2 | 1 | - | - |
Fali | 1 | - | 2 | 1 | - | - |
Victor Sanchez | 1 | - | 1 | 1 | - | - |
Victor Vazquez | 1 | - | 1 | 1 | - | - |
Marc Crosas | - | - | 2 | - | - | - |
Albert Jorquera | - | - | 7 | - | - | - |
Jose Rueda | - | - | 1 | - | - | - | 524 | 418 | 160 | 106 | 106 | 75 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .