| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Gael Clichy | 38 | 37 | 1 | 1 | 2 | - |
Emmanuel Adebayor | 36 | 32 | 4 | 4 | 9 | 24 |
Francesc Fabregas | 32 | 32 | - | - | 2 | 7 |
William Gallas | 31 | 31 | - | - | 1 | 4 |
Aliaksandr Hleb | 31 | 29 | 2 | 2 | 14 | 2 |
Mathieu Flamini | 30 | 30 | - | - | 4 | 3 |
Kolo Toure | 30 | 29 | 2 | 1 | 4 | 2 |
Bacary Sagna | 29 | 29 | - | - | 5 | 1 |
Manuel Almunia | 29 | 29 | 3 | - | - | - |
Nicklas Bendtner | 27 | 7 | 25 | 20 | 3 | 5 |
Theo Walcott | 25 | 11 | 18 | 14 | 5 | 4 |
Emmanuel Eboue | 23 | 20 | 4 | 3 | 12 | - |
Gilberto Silva | 23 | 12 | 16 | 11 | 1 | 1 |
Tomas Rosicky | 18 | 15 | 3 | 3 | 6 | 6 |
Philippe Senderos | 17 | 14 | 13 | 3 | 2 | 2 |
Eduardo da Silva | 17 | 13 | 5 | 4 | 8 | 4 |
Robin van Persie | 15 | 13 | 3 | 2 | 11 | 7 |
Abou Diaby | 15 | 9 | 7 | 6 | 4 | 1 |
Denilson | 13 | 4 | 11 | 9 | 1 | - |
Alex Song | 9 | 5 | 11 | 4 | - | - |
Jens Lehmann | 7 | 6 | 23 | 1 | - | - |
Lassana Diarra | 7 | 4 | 6 | 3 | 1 | - |
Justin Hoyte | 5 | 2 | 10 | 3 | 1 | - |
Lukasz Fabianski | 3 | 3 | 10 | - | 1 | - |
Armand Traore | 3 | 1 | 3 | 2 | 1 | - |
Johan Djourou | 2 | 1 | 3 | 1 | - | - |
Mark Randall | 1 | - | 1 | 1 | - | - |
Kieran Gibbs | - | - | 1 | - | - | - |
Kerrea Gilbert | - | - | 1 | - | - | - |
Vito Mannone | - | - | 2 | - | - | - |
Harvard Nordtveit | - | - | 1 | - | - | - |
Nacer Barazite | - | - | 1 | - | - | - | 516 | 418 | 190 | 98 | 98 | 73 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .