| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Richard Dunne | 36 | 36 | - | - | 2 | - |
Vedran Corluka | 35 | 34 | 3 | 1 | 3 | - |
Martin Petrov | 34 | 34 | - | - | 6 | 5 |
Blumer Elano | 34 | 29 | 5 | 5 | 23 | 8 |
Stephen Ireland | 33 | 32 | 2 | 1 | 17 | 4 |
Dietmar Hamann | 29 | 26 | 7 | 3 | 8 | - |
Michael Ball | 28 | 19 | 13 | 9 | - | - |
Darius Vassell | 27 | 21 | 6 | 6 | 15 | 6 |
Javier Garrido | 27 | 21 | 10 | 6 | 1 | - |
Joe Hart | 26 | 26 | 12 | - | - | - |
Gelson Fernandes | 26 | 21 | 8 | 5 | 1 | 2 |
Micah Richards | 25 | 25 | - | - | - | - |
Michael Johnson | 23 | 23 | - | - | 4 | 2 |
Rolando Bianchi | 19 | 7 | 12 | 12 | 5 | 4 |
Geovanni | 19 | 2 | 25 | 17 | 2 | 3 |
Nedum Onuoha | 16 | 13 | 10 | 3 | 1 | 1 |
Emile Mpenza | 15 | 8 | 7 | 7 | 7 | 2 |
Sun Jihai | 14 | 7 | 11 | 7 | - | - |
Benjani Mwaruwari | 13 | 13 | - | - | 4 | 3 |
Felipe Caicedo | 10 | - | 11 | 10 | - | - |
Kasper Schmeichel | 7 | 7 | 5 | - | - | - |
Nery Castillo | 7 | 2 | 8 | 5 | 2 | - |
Kelvin Etuhu | 6 | 2 | 4 | 4 | 2 | 1 |
Andreas Isaksson | 5 | 5 | 21 | - | - | - |
Georgios Samaras | 5 | 2 | 5 | 3 | 1 | - |
Daniel Sturridge | 3 | 2 | 1 | 1 | 3 | 1 |
Valeri Bojinov | 3 | 1 | 2 | 2 | 1 | - |
Sam Williamson | 1 | - | 1 | 1 | - | - |
Shaleum Logan | - | - | 1 | - | - | - | 526 | 418 | 190 | 108 | 108 | 42 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .