| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Ryan Babel | 12 | 6 | 6 | 6 | 2 | - |
Joris Mathijsen | 11 | 11 | - | - | - | 1 |
Giovanni van Bronckhorst | 10 | 10 | - | - | 2 | 1 |
Wesley Sneijder | 10 | 10 | - | - | 4 | 2 |
Andre Ooijer | 9 | 7 | 3 | 2 | 1 | - |
Edwin van der Sar | 8 | 8 | - | - | - | - |
Wilfred Bouma | 8 | 8 | - | - | 1 | - |
Robin van Persie | 7 | 7 | - | - | 3 | 4 |
Demy de Zeeuw | 7 | 6 | 4 | 1 | 2 | - |
Rafael van der Vaart | 7 | 5 | 1 | 2 | 1 | 1 |
Dirk Kuyt | 7 | 4 | 5 | 3 | 1 | 1 |
Urby Emanuelson | 7 | 2 | 8 | 5 | - | - |
John Heitinga | 6 | 6 | 5 | - | 3 | - |
Arjen Robben | 6 | 5 | 1 | 1 | 2 | - |
Denny Landzaat | 5 | 5 | - | - | 2 | - |
Clarence Seedorf | 5 | 3 | 4 | 2 | 2 | - |
Nigel De Jong | 5 | 3 | 6 | 2 | 1 | - |
Ruud van Nistelrooy | 4 | 4 | - | - | 1 | 2 |
Maarten Stekelenburg | 4 | 4 | 4 | - | - | - |
Mario Melchiot | 4 | 4 | - | - | 1 | - |
Klass - Jan Huntelaar | 4 | 4 | 3 | - | 1 | 1 |
Khalid Boulahrouz | 4 | 2 | 3 | 2 | - | - |
Stijn Schaars | 4 | 1 | 3 | 3 | 1 | - |
Danny Koevermans | 3 | 2 | 4 | 1 | 2 | 1 |
Kew Jaliens | 3 | 2 | 3 | 1 | - | - |
Tim de Cler | 2 | 1 | 1 | 1 | - | - |
Theo Janssen | 1 | 1 | 1 | - | - | - |
Ibrahim Afellay | 1 | 1 | - | - | 1 | - |
Jan Vennegoor of Hesselink | 1 | - | 6 | 1 | - | - |
Orlando Engelaar | 1 | - | 3 | 1 | - | - |
Henk Timmer | - | - | 8 | - | - | - |
Hedwiges Maduro | - | - | 2 | - | - | - | 166 | 132 | 84 | 34 | 34 | 14 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .