| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Nigel Reo-Coker | 35 | 35 | - | - | 6 | 1 |
Bobby Zamora | 32 | 27 | 7 | 5 | 19 | 11 |
Marlon Harewood | 32 | 19 | 13 | 13 | 12 | 3 |
Anton Ferdinand | 31 | 31 | - | - | 4 | - |
Hayden Mullins | 30 | 21 | 15 | 9 | 2 | 2 |
Yossi Benayoun | 29 | 25 | 6 | 4 | 6 | 3 |
Matthew Etherington | 27 | 24 | 3 | 3 | 9 | - |
Robert Green | 26 | 26 | 9 | - | - | - |
Carlos Tevez | 26 | 19 | 11 | 7 | 11 | 7 |
Jonathan Spector | 25 | 17 | 13 | 8 | 3 | - |
Paul Konchesky | 22 | 22 | - | - | 1 | - |
George McCartney | 22 | 16 | 9 | 6 | 3 | - |
Lee Bowyer | 20 | 18 | 3 | 2 | 7 | - |
Daniel Gabbidon | 18 | 18 | - | - | 4 | - |
Carlton Cole | 17 | 5 | 15 | 12 | 4 | 2 |
Teddy Sheringham | 17 | 4 | 15 | 13 | 3 | 2 |
James Collins | 16 | 16 | 2 | - | 1 | - |
Christian Dailly | 14 | 10 | 8 | 4 | - | - |
Luis Boa Morte | 14 | 8 | 6 | 6 | 2 | 1 |
Roy Carroll | 12 | 12 | 15 | - | - | - |
Lucas Neill | 11 | 11 | - | - | 1 | - |
Mark Noble | 10 | 10 | 1 | - | 2 | 2 |
Kepa Blanco | 8 | 1 | 7 | 7 | 1 | 1 |
Nigel Quashie | 7 | 7 | - | - | 2 | - |
Calum Davenport | 6 | 5 | 6 | 1 | - | - |
Javier Mascherano | 5 | 3 | 6 | 2 | 2 | - |
Tyrone Mears | 5 | 3 | 2 | 2 | 2 | - |
John Pantsil | 5 | 3 | 4 | 2 | - | - |
Shaun Newton | 3 | - | 3 | 3 | - | - |
Matthew Upson | 2 | 2 | - | - | 2 | - |
Jimmy Walker | - | - | 8 | - | - | - |
Gabor Kiraly | - | - | 3 | - | - | - | 527 | 418 | 190 | 109 | 109 | 35 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .