| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Nigel De Jong | 6 | 6 | - | - | 1 | 1 |
Rafael van der Vaart | 6 | 5 | 1 | 1 | 1 | 1 |
Wesley Sneijder | 6 | 5 | 1 | 1 | 2 | - |
Nicolae Mitea | 6 | 4 | 2 | 2 | 3 | 1 |
Zdenek Grygera | 5 | 5 | 1 | - | 2 | - |
Maxwell | 5 | 5 | - | - | - | - |
Anthony Obodai | 5 | 4 | 2 | 1 | 2 | - |
John Heitinga | 4 | 4 | - | - | 1 | - |
Hatem Trabelsi | 4 | 4 | - | - | - | - |
Mauro Rosales | 4 | 4 | - | - | 1 | - |
Wesley Sonck | 4 | 3 | 1 | 1 | 1 | 1 |
Julien Escude | 4 | 2 | 4 | 2 | - | - |
Nourdin Boukhari | 4 | 1 | 4 | 3 | 1 | - |
Steven Pienaar | 3 | 3 | 1 | - | 1 | - |
Tomas Galasek | 3 | 3 | - | - | 1 | 1 |
Daniel de Ridder | 3 | - | 6 | 3 | - | 1 |
Maarten Stekelenburg | 2 | 2 | 3 | - | - | - |
Bogdan Lobont | 2 | 2 | 1 | - | - | - |
Hans Vonk | 2 | 2 | 2 | - | - | - |
Ryan Babel | 2 | 2 | - | - | 1 | - |
Yannis Anastasiou | 2 | - | 6 | 2 | - | - |
Tom de Mul | 1 | - | 1 | 1 | - | - |
Stanley Aborah | 1 | - | 2 | 1 | - | - |
Thomas Vermaelen | - | - | 4 | - | - | - | 84 | 66 | 42 | 18 | 18 | 6 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .