| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Gary Neville | 32 | 32 | - | - | 1 | 1 |
Paul Scholes | 32 | 28 | 5 | 4 | 7 | 6 |
David Beckham | 31 | 29 | 3 | 2 | 3 | 9 |
Ryan Giggs | 31 | 24 | 9 | 7 | 4 | 5 |
Ole-Gunnar Solskjaer | 31 | 19 | 14 | 12 | 6 | 10 |
Fabian Barthez | 30 | 30 | - | - | 3 | - |
Mikael Silvestre | 30 | 25 | 8 | 5 | 3 | 1 |
Phil Neville | 29 | 24 | 12 | 5 | 4 | 1 |
Teddy Sheringham | 29 | 23 | 8 | 6 | 10 | 15 |
Roy Keane | 28 | 28 | - | - | 5 | 2 |
Wes Brown | 28 | 25 | 6 | 3 | 2 | - |
Nicky Butt | 28 | 24 | 6 | 4 | 9 | 3 |
Dwight Yorke | 22 | 15 | 12 | 7 | 5 | 9 |
Denis Irwin | 21 | 20 | 6 | 1 | 6 | - |
Andrew Cole | 19 | 15 | 6 | 4 | 6 | 9 |
Luke Chadwick | 16 | 6 | 13 | 10 | 4 | 2 |
Jaap Stam | 15 | 15 | 1 | - | 3 | - |
Ronnie Wallwork | 12 | 4 | 14 | 8 | 1 | - |
Ronny Johnsen | 11 | 11 | 1 | - | 3 | 1 |
Raimonde van der Gouw | 10 | 5 | 24 | 5 | - | - |
Quinton Fortune | 7 | 6 | 6 | 1 | 1 | 2 |
Jonathan Greening | 7 | 3 | 11 | 4 | 2 | - |
Michael Stewart | 3 | 3 | 1 | - | 2 | - |
Andy Goram | 2 | 2 | 3 | - | 2 | - |
David May | 2 | 1 | 2 | 1 | - | - |
Paul Rachubka | 1 | 1 | 6 | - | - | - |
Henning Berg | 1 | - | 1 | 1 | - | - |
Bojan Djordjic | 1 | - | 2 | 1 | - | - |
David Healy | 1 | - | 1 | 1 | - | - |
Mark Bosnich | - | - | 4 | - | - | - |
John O'Shea | - | - | 1 | - | - | - |
Michael Clegg | - | - | 2 | - | - | - |
Mark Wilson | - | - | 2 | - | - | - | 510 | 418 | 190 | 92 | 92 | 76 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .